SCHEMBL1409491

SCHEMBL1409491

CCCC(C)(C)CC(=O)Cl

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.43
TDP1 Q9NUW8 3/20 0.41
FFAR1 O14842 1/20 0.41
CPT2 P23786 1/20 0.41
ALDH1A1 P00352 4/20 0.40
TP53 P04637 1/20 0.40
FDPS P14324 2/20 0.36
LMNA P02545 1/20 0.35
HSD17B10 Q99714 1/20 0.35
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
KDM4E B2RXH2 1/20 0.31
HMGCR P04035 1/20 0.31
CHRM1 P11229 1/20 0.31
TBXA2R P21731 1/20 0.31
ADRA1A P35348 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1410643 0.85 FFAR1 (0.48) TSHRTDP1FFAR1CPT2ALDH1A1
SCHEMBL1410746 0.83 FFAR1 (0.52) TSHRTDP1FFAR1CPT2ALDH1A1
SCHEMBL665258 0.83 TSHR (0.45) TSHRTDP1FFAR1CPT2ALDH1A1
SCHEMBL27941651 0.82 FFAR1 (0.39) TSHRTDP1FFAR1CPT2ALDH1A1
SCHEMBL8110273 0.81 FFAR1 (0.56) TSHRTDP1FFAR1CPT2ALDH1A1
SCHEMBL11288621 0.81 FFAR1 (0.56) TSHRTDP1FFAR1CPT2ALDH1A1
SCHEMBL1114714 0.81 FFAR1 (0.56) TSHRTDP1FFAR1CPT2ALDH1A1
SCHEMBL11566635 0.81 TDP1 (0.42) TSHRTDP1FFAR1CPT2ALDH1A1
SCHEMBL8881988 0.80 FFAR1 (0.38) TSHRTDP1FFAR1CPT2ALDH1A1
SCHEMBL974936 0.79 FFAR1 (0.65) TSHRTDP1FFAR1CPT2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630521-B2 Arylamides and methods of use thereof GENZYME CORPORATION (US) 2026-05-19 US disclosed
US-12630498-B2 Arylamides and methods of use thereof GENZYME CORPORATION (US) 2026-05-19 US disclosed
US-20230159438-A1 ARYLAMIDES AND METHODS OF USE THEREOF GENZYME CORPORATION 2023-05-25 US disclosed
US-20230147360-A1 ARYLAMIDES AND METHODS OF USE THEREOF GENZYME CORPORATION 2023-05-11 US disclosed
WO-2021113809-A1 ARYLAMIDES AND METHODS OF USE THEREOF GENZYME CORPORATION (US) 2021-06-10 WO disclosed
WO-2021113806-A1 ARYLAMIDES AND METHODS OF USE THEREOF GENZYME CORPORATION (US) 2021-06-10 WO disclosed
CN-102471384-B Cellulose derivative, resin composition, molded body, method for producing molded body, and housing for electric and electronic devices FUJIFILM CORP 2015-06-17 CN disclosed
CN-102471539-B Cellulose derivative, thermoformed material, molded body, production method therefor, and casing for electrical and electronic equipment FUJIFILM CORP 2015-04-08 CN disclosed
EP-2295470-B1 CELLULOSE DERIVATIVE AND PROCESS FOR PRODUCTION THEREOF, CELLULOSE RESIN COMPOSITION, MOLDED ARTICLE AND METHOD FOR PRODUCTION THEREOF, AND HOUSING FOR ELECTROCHEMICAL DEVICE FUJIFILM CORP (JP) 2014-06-18 EP disclosed
CN-102076718-B Cellulose derivative and process for production thereof, cellulose resin composition, molded article and method for production thereof, and housing for electrochemical device FUJIFILM CORP 2013-10-23 CN disclosed
CN-102471384-A Cellulose derivative, resin composition, molded body, method for producing molded body, and housing for electric and electronic devices FUJIFILM CORP 2012-05-23 CN disclosed
CN-102471539-A Cellulose derivative, thermoformed material, molded body, production method therefor, and casing for electrical and electronic equipment FUJIFILM CORP 2012-05-23 CN disclosed
CN-102076718-A Cellulose derivative and process for production thereof, cellulose resin composition, molded article and method for production thereof, and housing for electrochemical device FUJIFILM CORP 2011-05-25 CN disclosed
US-20110098463-A1 CELLULOSE DERIVATIVE AND METHOD FOR PRODUCING THE SAME, CELLULOSE RESIN COMPOSITION, MOLDED MATTER AND METHOD FOR MAKING THE SAME, AND ELECTRICAL AND ELECTRONIC EQUIPMENT HOUSING FUJIFILM CORPORATION (JP) 2011-04-28 US disclosed
EP-2295470-A1 CELLULOSE DERIVATIVE AND PROCESS FOR PRODUCTION THEREOF, CELLULOSE RESIN COMPOSITION, MOLDED ARTICLE AND METHOD FOR PRODUCTION THEREOF, AND HOUSING FOR ELECTROCHEMICAL DEVICE FUJIFILM Corporation (JP) 2011-03-16 EP disclosed
CN-1946391-A Combinations comprising alpha-2-delta ligands PFIZER PROD INC (US) 2007-04-11 CN disclosed
WO-2004056768-A2 USE OF SUBSTITUTED 2,5-DIAMIDOINDOLES FOR THE TREATMENT OF UROLOGICAL DISEASES BAYER HEALTHCARE AG (DE) 2004-07-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230147360-A1 ARYLAMIDES AND METHODS OF USE THEREOF CFTR, AADAC, ARSA TSHR 2786/4885TDP1 3414/4885FFAR1 3376/4885
US-20230159438-A1 ARYLAMIDES AND METHODS OF USE THEREOF CFTR, AADAC, ARSA TSHR 2786/4885TDP1 3414/4885FFAR1 3376/4885
US-12630521-B2 Arylamides and methods of use thereof CFTR, CLIC1, CLCN2 TSHR 497/4885TDP1 4402/4885FFAR1 2122/4885
US-12630498-B2 Arylamides and methods of use thereof CFTR, CLIC1, CLCN2 TSHR 337/4885TDP1 4457/4885FFAR1 1382/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.