SCHEMBL140950

SCHEMBL140950

c1coc(CSCc2ccco2)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.59
ALDH1A1 P00352 15/20 0.53
MAPT P10636 8/20 0.53
POLB P06746 7/20 0.53
TDP1 Q9NUW8 5/20 0.53
HPGD P15428 6/20 0.50
NPC1 O15118 5/20 0.50
RAB9A P51151 5/20 0.50
HSD17B10 Q99714 5/20 0.50
KDM4E B2RXH2 3/20 0.50
LMNA P02545 1/20 0.50
SMN1; SMN2 Q16637 4/20 0.49
L3MBTL1 Q9Y468 4/20 0.49
KMT2A Q03164 2/20 0.47
MEN1 O00255 1/20 0.47
ALOX12 P18054 1/20 0.47
PTPN7 P35236 1/20 0.43
USP2 O75604 1/20 0.43
CHRM2 P08172 1/20 0.42
ALOX15 P16050 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4434792 0.88
SCHEMBL29281809 0.87 TSHR (0.68) TSHRALDH1A1MAPTPOLBTDP1
SCHEMBL9697427 0.86
SCHEMBL3940524 0.86
SCHEMBL25435114 0.85 TSHR (0.47) TSHRALDH1A1MAPTPOLBTDP1
Ammonia Solution, Strong SCHEMBL10914529 0.84 ALDH1A1 (0.50) TSHRALDH1A1MAPTPOLBTDP1
SCHEMBL4869503 0.84 ALDH1A1 (0.54) TSHRALDH1A1MAPTPOLBTDP1
SCHEMBL891217 0.84 TSHR (0.46) TSHRALDH1A1MAPTPOLBTDP1
SCHEMBL6130008 0.83 ALDH1A1 (0.57) TSHRALDH1A1MAPTPOLBTDP1
SCHEMBL10685820 0.83 ALDH1A1 (0.53) TSHRALDH1A1MAPTPOLBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 516 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3890471-B1 BIODEGRADABLE FOAM SUBSTRATE FOR GROWING PLANTS, PLANT SYSTEM PROVIDED THEREWITH, AND METHOD FOR MANUFACTURING SUCH SUBSTRATE FOAMPLANT B V (NL) 2026-05-06 EP claimed
EP-4444108-B1 ALDEHYDE MIXTURES FOR FLAVOUR IMPROVEMENT SYMRISE AG (DE) 2025-09-10 EP claimed
CN-120142551-A Quantification method of exogenous essence and spice in sesame oil 武汉食品化妆品检验所 2025-06-13 CN claimed
CN-119924491-A Flavoring composition with balanced taste characteristics 西姆莱斯有限公司 2025-05-06 CN claimed
CN-119752357-A Low-VOC gas volatilization high-temperature-resistant hot melt adhesive composite film and preparation method thereof 江苏惠沣环保科技有限公司 2025-04-04 CN claimed
CN-113921448-B Fitting body 古河电气工业株式会社 2025-03-25 CN claimed
CN-119661890-A Preparation method and application of difurfuryl thioether long-chain branching modified polypropylene roughened film for extremely-cold-resistant oil-immersed capacitor 哈尔滨理工大学 2025-03-21 CN claimed
CN-119569951-A Preparation method and application of high melt strength polypropylene 国网黑龙江省电力有限公司电力科学研究院 2025-03-07 CN claimed
CN-119423282-A Pickled vaccinium uliginosum fresh flavor essence prepared based on green bamboo shoot extract 天津春发生物科技集团有限公司 2025-02-14 CN claimed
EP-4474483-A1 METHOD FOR SCREENING SUBSTANCE THAT SUPPRESSES 4-METHYLACETOPHENONE ODOR, AND METHOD FOR SUPPRESSING 4-METHYL ACETOPHENONE ODOR AJINOMOTO CO., INC. (JP) 2024-12-11 EP claimed
US-6872754-B1 Method for processing elastomers WORTHAM LEON (US) 2005-03-29 US claimed
WO-2004039819-A2 METHOD FOR THE PRODUCTION OF COMPOUNDS CONTAINING PALLADIUM (0) UMICORE AG & CO. KG (DE) 2004-05-13 WO claimed
US-6686495-B2 IN PRESENCE OF PALLADIUM CATALYST; USEFUL IN PRODUCING CHEMICAL INTERMEDIATES FOR PHARMACEUTICALS, OPTICAL BRIGHTENING AGENTS AND AGROCHEMICALS OMG AG & CO KG (DE) 2004-02-03 US claimed
US-20020107426-A1 Process for the preparation of mono-, bi- or poly- functional biaryls UMICORE AG & CO. KG (DE) 2002-08-08 US claimed
EP-1199292-A1 Process for the production of mono-, bi- or polyfunctional biaryls OMG AG & Co. KG (DE) 2002-04-24 EP claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107426-A1 Process for the preparation of mono-, bi- or poly- functional biaryls CYP4F3, CYP4F2, CYP2F1 TSHR 3712/4885ALDH1A1 714/4885MAPT 3645/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.