Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 9/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14095529 | 0.92 | CYP11B1 (0.37) | CYP11B2CYP11B1HRH3CYP3A4CYP2D6 | |
| SCHEMBL14095252 | 0.89 | HRH3 (0.34) | HRH3CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL14095521 | 0.88 | HRH3 (0.46) | HRH3CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL14095167 | 0.87 | CYP11B2 (0.38) | CYP11B2CYP11B1CYP3A4CYP2D6 | |
| SCHEMBL13319372 | 0.85 | HRH3 (0.44) | CYP11B2HRH3CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL14095225 | 0.85 | USP2 (0.34) | HRH3CYP3A4CYP2D6 | |
| SCHEMBL14095143 | 0.82 | HRH3 (0.38) | HRH3CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL14258948 | 0.82 | HRH3 (0.44) | HRH3CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL13319280 | 0.80 | HRH3 (0.48) | HRH3CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL13319354 | 0.79 | CYP3A4 (0.48) | CYP11B2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008108958-A2 | BENZIMIDAZOLE DERIVATIVES AND METHODS OF USE THEREOF | SCHERING CORPORATION (US) | 2008-09-12 | — | — | WO | disclosed |