Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CCR6 | P51684 | 3/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14095784 | 0.86 | MEN1 (0.48) | MEN1KMT2ACCR6ADRB3ADRB1 | |
| SCHEMBL14095883 | 0.79 | ADRB3 (0.46) | MEN1KMT2ACCR6ADRB3ADRB1 | |
| SCHEMBL3299350 | 0.79 | MAPT (0.41) | MEN1KMT2ACCR6PKMSMN1; SMN2 | |
| SCHEMBL2262940 | 0.78 | KDM1A (0.60) | KDM1AMAOAMAOB | |
| SCHEMBL14095785 | 0.78 | KMT2A (0.56) | MEN1KMT2ACCR6PKMSMN1; SMN2 | |
| SCHEMBL14095878 | 0.73 | EBP (0.56) | MEN1KMT2APKMSMN1; SMN2HTT | |
| SCHEMBL14095860 | 0.73 | HTT (0.48) | MEN1KMT2ACCR6PKMSMN1; SMN2 | |
| SCHEMBL14095881 | 0.72 | KMT2A (0.55) | MEN1KMT2APKMSMN1; SMN2MAPT | |
| SCHEMBL14095783 | 0.72 | KMT2A (0.49) | MEN1KMT2AADRB3ADRB1KDM1A | |
| SCHEMBL14095875 | 0.71 | PKM (0.57) | MEN1KMT2APKMSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008099073-A1 | N, N' -2, 4-DIANILINOPYRIMIDINES PREPARATION AND USE THEREOF AS IKK INHIBITORS PREPARATION AND TEH PHARMACUETICAL COMPOSITIONS THEREOF | SANOFI-AVENTIS (FR) | 2008-08-21 | — | — | WO | disclosed |