Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 18/20 | 1.00 |
| ▸ | FLT1 | P17948 | 18/20 | 1.00 |
| ▸ | KDR | P35968 | 18/20 | 1.00 |
| ▸ | EGFR | P00533 | 14/20 | 1.00 |
| ▸ | FLT4 | P35916 | 14/20 | 1.00 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.70 |
| ▸ | TEK | Q02763 | 2/20 | 0.70 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.70 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.70 |
| ▸ | EPHB2 | P29323 | 2/20 | 0.70 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.70 |
| ▸ | PLK4 | O00444 | 1/20 | 0.70 |
| ▸ | CIT | O14578 | 1/20 | 0.70 |
| ▸ | GAK | O14976 | 1/20 | 0.70 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.70 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.70 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.70 |
| ▸ | STK10 | O94804 | 1/20 | 0.70 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.70 |
| ▸ | ABL1 | P00519 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2137353 | 0.92 | EGFR (0.98) | FGFR1FLT1KDREGFRFLT4 | |
| SCHEMBL27218222 | 0.91 | EGFR (1.00) | FGFR1FLT1KDREGFRFLT4 | |
| Hydrochloric Acid SCHEMBL2140851 | 0.91 | EGFR (1.00) | FGFR1FLT1KDREGFRFLT4 | |
| SCHEMBL5433644 | 0.89 | FLT1 (0.83) | FGFR1FLT1KDREGFRFLT4 | |
| SCHEMBL7864669 | 0.87 | KDR (1.00) | FGFR1FLT1KDREGFRFLT4 | |
| SCHEMBL1885485 | 0.87 | FGFR1 (0.77) | FGFR1FLT1KDREGFRFLT4 | |
| SCHEMBL5428945 | 0.87 | FLT1 (0.77) | FGFR1FLT1KDREGFRFLT4 | |
| SCHEMBL7867152 | 0.86 | KDR (0.98) | FGFR1FLT1KDREGFRFLT4 | |
| SCHEMBL1467367 | 0.86 | FGFR1 (1.00) | FGFR1FLT1KDREGFRFLT4 | |
| SCHEMBL3136293 | 0.86 | EGFR (0.85) | FGFR1FLT1KDREGFRFLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240156825-A1 | USE OF SELECTIVE VEGFR2 AND FGFR1 INHIBITORS | FOUNTAIN THERAPEUTICS INC (US) | 2024-05-16 | — | — | US | disclosed |
| US-20080199480-A1 | Methods for Identifying Risk of Type II Diabetes and Treatments Thereof | SEQUENOM, INC. (US) | 2008-08-21 | — | — | US | disclosed |
| US-20080199480-A1 | Methods for Identifying Risk of Type II Diabetes and Treatments Thereof | SEQUENOM, INC. (US) | 2008-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080199480-A1 | Methods for Identifying Risk of Type II Diabetes and Treatments Thereof | SLC5A2, GCKR, IAPP | FGFR1 3131/4885FLT1 3662/4885KDR 2859/4885 |
| US-20240156825-A1 | USE OF SELECTIVE VEGFR2 AND FGFR1 INHIBITORS | FGFR1, FRS2, FGFR2 | FGFR1 1/4885FLT1 4/4885KDR 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.