SCHEMBL1409644

SCHEMBL1409644

CC(NS(=O)(=O)CCCOCn1ccc(=O)[nH]c1=O)c1ccc(F)c(OCC(F)F)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DUT P33316 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1409641 1.00 DUT (1.00) DUT
SCHEMBL1409284 0.89 DUT (1.00) DUT
SCHEMBL1409286 0.89 DUT (1.00) DUT
SCHEMBL1409517 0.88 DUT (1.00) DUT
SCHEMBL1409515 0.88 DUT (1.00) DUT
SCHEMBL1409482 0.87 DUT (1.00) DUT
SCHEMBL1409483 0.87 DUT (1.00) DUT
SCHEMBL1409451 0.86 DUT (1.00) DUT
SCHEMBL1409453 0.86 DUT (1.00) DUT
SCHEMBL12632785 0.85 DUT (0.74) DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2508185-B1 ANTI-TUMOR EFFECT POTENTIATOR TAIHO PHARMACEUTICAL CO LTD (JP) 2020-03-04 EP claimed
US-8883759-B2 Anti-tumor effect potentiator TAIHO PHARMACEUTICAL CO., LTD. (JP) 2014-11-11 US claimed
US-20120225838-A1 ANTI-TUMOR EFFECT POTENTIATOR TAIHO PHARMACEUTICAL CO., LTD. (JP) 2012-09-06 US claimed
EP-3673908-B1 ANTI-TUMOR EFFECT POTENTIATOR TAIHO PHARMACEUTICAL CO LTD (JP) 2022-01-12 EP disclosed
EP-3673908-A1 ANTI-TUMOR EFFECT POTENTIATOR Taiho Pharmaceutical Co., Ltd. (JP) 2020-07-01 EP disclosed
EP-2508185-B1 ANTI-TUMOR EFFECT POTENTIATOR TAIHO PHARMACEUTICAL CO LTD (JP) 2020-03-04 EP disclosed
US-8883759-B2 Anti-tumor effect potentiator TAIHO PHARMACEUTICAL CO., LTD. (JP) 2014-11-11 US disclosed
US-8530490-B2 Uracil compound or salt thereof having human deoxyuridine triphosphatase inhibitory activity TAIHO PHARMACEUTICAL CO., LTD. (JP) 2013-09-10 US disclosed
EP-2508185-A1 ANTI-TUMOR EFFECT POTENTIATOR Taiho Pharmaceutical Co., Ltd. (JP) 2012-10-10 EP disclosed
EP-2295414-B1 URACIL COMPOUND HAVING INHIBITORY ACTIVITY ON HUMAN DEOXYURIDINE TRIPHOSPHATASE OR SALT THEREOF TAIHO PHARMACEUTICAL CO LTD (JP) 2012-09-26 EP disclosed
US-20120225838-A1 ANTI-TUMOR EFFECT POTENTIATOR TAIHO PHARMACEUTICAL CO., LTD. (JP) 2012-09-06 US disclosed
US-20110082163-A1 NOVEL URACIL COMPOUND OR SALT THEREOF HAVING HUMAN DEOXYURIDINE TRIPHOSPHATASE INHIBITORY ACTIVITY TAIHO PHARMACEUTICAL CO., LTD. (JP) 2011-04-07 US disclosed
EP-2295414-A1 NOVEL URACIL COMPOUND HAVING INHIBITORY ACTIVITY ON HUMAN DEOXYURIDINE TRIPHOSPHATASE OR SALT THEREOF Taiho Pharmaceutical Co., Ltd. (JP) 2011-03-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120225838-A1 ANTI-TUMOR EFFECT POTENTIATOR CCNT1, CCNA1, UPP1 DUT 305/4885
US-20110082163-A1 NOVEL URACIL COMPOUND OR SALT THEREOF HAVING HUMAN DEOXYURIDINE TRIPHOSPHATASE INHIBITORY ACTIVITY SNRPB2, SNRPA1, DUT DUT 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.