Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 17/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14097512 | 0.88 | ABL1 (0.50) | ABL1 | |
| SCHEMBL5075903 | 0.80 | ABL1 (0.82) | ABL1 | |
| SCHEMBL5036031 | 0.78 | MET (0.56) | ABL1 | |
| SCHEMBL14395379 | 0.78 | ABL1 (0.53) | ABL1 | |
| SCHEMBL14097584 | 0.77 | ABL1 (0.64) | ABL1 | |
| SCHEMBL14097395 | 0.77 | ABL1 (0.62) | ABL1 | |
| SCHEMBL14097614 | 0.77 | ABL1 (0.84) | ABL1 | |
| SCHEMBL14097574 | 0.76 | ABL1 (0.59) | ABL1 | |
| SCHEMBL14097588 | 0.76 | ABL1 (0.61) | ABL1 | |
| SCHEMBL14097445 | 0.76 | ABL1 (0.58) | ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7414046-B2 | Gyrase inhibitors and uses thereof | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2008-08-19 | — | — | US | disclosed |
| US-7414046-B2 | Gyrase inhibitors and uses thereof | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2008-08-19 | — | — | US | disclosed |