SCHEMBL1409830

SCHEMBL1409830

NC(=O)c1ccccc1NC(=O)O

nearest known ligand 0.67

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.64
ALDH1A1 P00352 4/20 0.64
HPGD P15428 1/20 0.64
PDCD1 Q15116 1/20 0.62
CD274 Q9NZQ7 1/20 0.62
POLB P06746 2/20 0.57
SMN1; SMN2 Q16637 2/20 0.57
LMNA P02545 2/20 0.56
SIRT2 Q8IXJ6 3/20 0.54
NPC1 O15118 2/20 0.54
RAB9A P51151 2/20 0.54
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
TP53 P04637 1/20 0.53
GLA P06280 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5365142 0.87 KDM4E (0.65) KDM4EALDH1A1HPGDPDCD1CD274
SCHEMBL7848398 0.84 KDM4E (0.60) KDM4EALDH1A1HPGDPDCD1CD274
SCHEMBL23249603 0.84 KDM4E (0.47) KDM4EALDH1A1HPGDPDCD1CD274
SCHEMBL211260 0.83 KMT2A (0.61) KDM4EALDH1A1POLBLMNAMEN1
SCHEMBL786246 0.82 PDCD1 (0.81) KDM4EALDH1A1HPGDPDCD1CD274
SCHEMBL894741 0.82 SIRT2 (0.70) KDM4EALDH1A1HPGDPDCD1CD274
SCHEMBL30139987 0.82 KDM4E (0.60) KDM4EALDH1A1HPGDPDCD1CD274
SCHEMBL27971661 0.82 KDM4E (0.59) KDM4EALDH1A1HPGDPDCD1CD274
SCHEMBL45762 0.82 KDM4E (0.60) KDM4EALDH1A1HPGDPDCD1CD274
SCHEMBL3644391 0.81 MEN1 (0.70) KDM4EALDH1A1POLBSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117617241-A Coated double-carrier pesticide controlled release granule and preparation method and application thereof 安徽农业大学 2024-03-01 CN claimed
CN-112469687-B New method for preparing o-carboxamido benzamide compound PI工业有限公司 2023-10-13 CN disclosed
CN-116670115-A Process for preparing anthranilic acid/anthranilic acid amide compounds and intermediates thereof 皮埃企业有限公司 2023-08-29 CN disclosed
CN-114737209-A Method for preparing 2-formamido benzamide derivative through continuous electrochemical reaction 南京先进生物材料与过程装备研究院有限公司 2022-07-12 CN disclosed
CN-107278209-B Catalyst components for the polymerization of olefins 巴塞尔聚烯烃意大利有限公司 2020-03-10 CN disclosed
CN-109627239-A The inhibitor of fibroblast growth factor acceptor 蓝印药品公司 2019-04-16 CN disclosed
CN-104540809-B Inhibitors of fibroblast growth factor receptors 蓝印药品公司 2018-12-11 CN disclosed
CN-104540809-A Inhibitors of fibroblast growth factor receptors BLUEPRINT MEDICINES 2015-04-22 CN disclosed
EP-2300483-A1 TRIAZINE COMPOUNDS AS P13 KINASE AND MTOR INHIBITORS Wyeth LLC (US) 2011-03-30 EP disclosed
EP-2294072-A1 TRIAZINE COMPOUNDS AS P13 KINASE AND MTOR INHIBITORS Wyeth LLC (US) 2011-03-16 EP disclosed
WO-2009143317-A1 TRIAZINE COMPOUNDS AS P13 KINASE AND MTOR INHIBITORS WYETH (US) 2009-11-26 WO disclosed
WO-2009143313-A1 TRIAZINE COMPOUNDS AS P13 KINASE AND MTOR INHIBITORS WYETH (US) 2009-11-26 WO disclosed
US-6083876-A Effect of herbicides CULTOR CORPORATION (FI) 2000-07-04 US disclosed