Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.57 |
| ▸ | HTR2A | P28223 | 6/20 | 0.49 |
| ▸ | HTR2C | P28335 | 4/20 | 0.49 |
| ▸ | HTR1A | P08908 | 4/20 | 0.46 |
| ▸ | HTR2B | P41595 | 4/20 | 0.46 |
| ▸ | HTR1D | P28221 | 2/20 | 0.46 |
| ▸ | HTR1B | P28222 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HTR1E | P28566 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23259357 | 0.83 | GPR84 (0.65) | GPR84HTR2AHTR2CHTR1AHTR2B | |
| SCHEMBL30811413 | 0.82 | HTR2A (0.69) | GPR84HTR2AHTR2CHTR1AHTR2B | |
| SCHEMBL29280816 | 0.82 | HTR2A (0.69) | GPR84HTR2AHTR2CHTR1AHTR2B | |
| SCHEMBL24912883 | 0.82 | HTR2A (0.69) | GPR84HTR2AHTR2CHTR1AHTR2B | |
| SCHEMBL5764881 | 0.82 | HTR2A (0.69) | GPR84HTR2AHTR2CHTR1ASLC6A4 | |
| SCHEMBL13962418 | 0.82 | HTR2A (0.69) | GPR84HTR2AHTR2CHTR1ASLC6A4 | |
| SCHEMBL4603380 | 0.81 | GPR84 (0.57) | GPR84HTR2AHTR2CHTR1AHTR2B | |
| SCHEMBL22122335 | 0.76 | GPR84 (0.59) | GPR84HTR2AHTR2CHTR1AHTR2B | |
| SCHEMBL27220736 | 0.76 | GPR84 (0.50) | GPR84HTR2AHTR2CHTR1AHTR2B | |
| SCHEMBL27220732 | 0.76 | GPR84 (0.50) | GPR84HTR2AHTR2CHTR1AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1956016-A1 | Bicyclic acyltryptophanols | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-08-13 | — | — | EP | disclosed |