SCHEMBL14099790

SCHEMBL14099790

c1ccc(-c2c3ccc(N(c4ccccc4)c4ccccc4)cc3c(-c3ccc4ccc5ccccc5c4c3)c3ccc(N(c4ccccc4)c4ccccc4)cc23)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.38
CYP1B1 Q16678 4/20 0.38
HSD17B10 Q99714 3/20 0.38
HIF1A Q16665 1/20 0.38
HPRT1 P00492 3/20 0.36
ESR1 P03372 3/20 0.36
ESR2 Q92731 3/20 0.36
TDP1 Q9NUW8 2/20 0.34
TSHR P16473 2/20 0.34
CYP2A6 P11509 1/20 0.34
SOS1 Q07889 1/20 0.33
ALOX5 P09917 1/20 0.33
CYP1A2 P05177 4/20 0.33
CYP3A4 P08684 3/20 0.33
CYP2D6 P10635 3/20 0.33
CYP2C9 P11712 3/20 0.33
CYP2C19 P33261 3/20 0.33
MAPT P10636 3/20 0.33
KDM4E B2RXH2 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12014691 0.97 ALDH1A1 (0.40) ALDH1A1CYP1B1HSD17B10HIF1AHPRT1
SCHEMBL14099793 0.96 ESR1 (0.38) ALDH1A1CYP1B1HSD17B10HIF1AHPRT1
SCHEMBL12014695 0.96 ALDH1A1 (0.39) ALDH1A1CYP1B1HSD17B10HIF1AHPRT1
SCHEMBL14099792 0.96 ALDH1A1 (0.41) ALDH1A1CYP1B1HSD17B10HIF1AHPRT1
SCHEMBL15762799 0.96 ALDH1A1 (0.41) ALDH1A1CYP1B1HSD17B10HIF1AHPRT1
SCHEMBL12014697 0.93 ALDH1A1 (0.37) ALDH1A1CYP1B1HSD17B10HIF1AHPRT1
SCHEMBL13015753 0.93 ALDH1A1 (0.44) ALDH1A1CYP1B1HSD17B10HIF1AHPRT1
SCHEMBL12014699 0.92 CYP1B1 (0.34) ALDH1A1CYP1B1HSD17B10HIF1AHPRT1
SCHEMBL12014702 0.91 ALDH1A1 (0.40) ALDH1A1CYP1B1HSD17B10HIF1AHPRT1
SCHEMBL14100088 0.91 ALDH1A1 (0.35) ALDH1A1CYP1B1HSD17B10HIF1AHPRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9620721-B2 OLEDs having high efficiency and excellent lifetime GLOBAL OLED TECHNOLOGY LLC (US) 2017-04-11 US disclosed
US-9620721-B2 OLEDs having high efficiency and excellent lifetime GLOBAL OLED TECHNOLOGY LLC (US) 2017-04-11 US disclosed
US-8795855-B2 OLEDs having high efficiency and excellent lifetime GLOBAL OLED TECHNOLOGY LLC (US) 2014-08-05 US disclosed
US-8795855-B2 OLEDs having high efficiency and excellent lifetime GLOBAL OLED TECHNOLOGY LLC (US) 2014-08-05 US disclosed
US-20140151676-A1 OLEDS HAVING HIGH EFFICIENCY AND EXCELLENT LIFETIME GLOBAL OLED TECHNOLOGY LLC (US) 2014-06-05 US disclosed
US-20140151676-A1 OLEDS HAVING HIGH EFFICIENCY AND EXCELLENT LIFETIME GLOBAL OLED TECHNOLOGY LLC (US) 2014-06-05 US disclosed
US-20080182129-A1 OLEDS HAVING HIGH EFFICIENCY AND EXCELLENT LIFETIME GLOBAL OLED TECHNOLOGY LLC 2008-07-31 US disclosed
US-20080182129-A1 OLEDS HAVING HIGH EFFICIENCY AND EXCELLENT LIFETIME GLOBAL OLED TECHNOLOGY LLC 2008-07-31 US disclosed