Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | AGXT | P21549 | 2/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14100040 | 0.95 | SMN1; SMN2 (0.62) | GFERKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL14099957 | 0.89 | SMN1; SMN2 (0.55) | GFERKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL14099960 | 0.84 | SMN1; SMN2 (0.65) | GFERKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL12779299 | 0.82 | MRGPRX4 (0.47) | GFERKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL14099985 | 0.81 | NPC1 (0.52) | NPC1RAB9ACYP3A4IDO1AGXT | |
| SCHEMBL14099976 | 0.78 | NPC1 (0.49) | GFERKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL12779267 | 0.77 | MRGPRX4 (0.44) | GFERKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL14100042 | 0.76 | SMN1; SMN2 (0.65) | GFERKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL12779279 | 0.76 | MRGPRX4 (0.44) | NPC1RAB9AIDO1NR4A2MAOB | |
| SCHEMBL12778472 | 0.75 | NPC1 (0.41) | NPC1RAB9ACYP3A4NR4A2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799636-B1 | CONTROL OF PARASITES IN ANIMALS BY THE USE OF NOVEL TRIFLUOROMETHANESULFONANILIDE OXIME ETHER DERIVATIVES | SCHERING PLOUGH LTD (CH) | 2008-08-27 | — | — | EP | disclosed |