Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | AGXT | P21549 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 6/20 | 0.42 |
| ▸ | MAOA | P21397 | 3/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
| ▸ | FADS1 | O60427 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14099976 | 0.92 | NPC1 (0.49) | NPC1RAB9APPARGPPARANOS2 | |
| SCHEMBL14100001 | 0.88 | IDO1 (0.45) | NPC1RAB9APPARGPPARAIDO1 | |
| SCHEMBL14100007 | 0.82 | MAPT (0.48) | NPC1RAB9APPARGPPARACYP3A4 | |
| SCHEMBL14099993 | 0.81 | PPARG (0.42) | NPC1RAB9APPARGPPARAIDO1 | |
| SCHEMBL12779105 | 0.81 | NPC1 (0.49) | NPC1RAB9APPARGPPARACYP3A4 | |
| SCHEMBL14100014 | 0.81 | GFER (0.59) | NPC1RAB9APPARGPPARACYP3A4 | |
| SCHEMBL14099986 | 0.81 | SMN1; SMN2 (0.40) | NPC1RAB9ACYP3A4NOS2MAPT | |
| SCHEMBL14100081 | 0.80 | L3MBTL1 (0.40) | NPC1RAB9APPARGPPARANOS2 | |
| SCHEMBL25923623 | 0.78 | CYP3A4 (0.55) | NPC1RAB9APPARGPPARACYP3A4 | |
| SCHEMBL14100105 | 0.77 | NOS2 (0.42) | RAB9ACYP3A4NOS2FADS1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799636-B1 | CONTROL OF PARASITES IN ANIMALS BY THE USE OF NOVEL TRIFLUOROMETHANESULFONANILIDE OXIME ETHER DERIVATIVES | SCHERING PLOUGH LTD (CH) | 2008-08-27 | — | — | EP | disclosed |