Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | PTPRC | P08575 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6925841 | 0.82 | TSHR (0.63) | MAPK1TSHRLMNA | |
| SCHEMBL24142683 | 0.81 | KMT2A (0.56) | KMT2AMEN1PTPN1PTPRCALDH1A1 | |
| SCHEMBL19795773 | 0.80 | KMT2A (0.59) | KMT2AMEN1PTPN1PTPRCALDH1A1 | |
| SCHEMBL19695641 | 0.80 | KMT2A (0.54) | KMT2AMEN1PTPN1PTPRCALDH1A1 | |
| SCHEMBL3296385 | 0.79 | ALDH1A1 (0.57) | KMT2AMEN1PTPN1PTPRCALDH1A1 | |
| SCHEMBL16626106 | 0.79 | PTPN1 (0.51) | KMT2AMEN1PTPN1PTPRCALDH1A1 | |
| SCHEMBL14783691 | 0.79 | KMT2A (0.57) | KMT2AMEN1PTPN1PTPRCALDH1A1 | |
| SCHEMBL14855865 | 0.79 | KMT2A (0.57) | KMT2AMEN1PTPN1PTPRCALDH1A1 | |
| SCHEMBL2241428 | 0.79 | KMT2A (0.57) | KMT2AMEN1PTPN1PTPRCALDH1A1 | |
| SCHEMBL543540 | 0.78 | ALDH1A1 (0.55) | KMT2AMEN1PTPN1PTPRCALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7414078-B2 | Oral general anesthetics and metabolitically resistant anticonvulsants | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2008-08-19 | — | — | US | disclosed |