Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | NEU3 | Q9UQ49 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8170889 | 0.86 | MAPT (0.48) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL20726340 | 0.73 | ALDH1A1 (0.51) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL38666282 | 0.71 | ALDH1A1 (0.56) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL21433102 | 0.71 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL8332038 | 0.70 | KDM4E (0.63) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL3201580 | 0.70 | ALDH1A1 (0.48) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL3513570 | 0.70 | MAPT (0.57) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL28836945 | 0.69 | MAPT (0.53) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL11921499 | 0.69 | ALDH1A1 (0.57) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL17010325 | 0.68 | ALDH1A1 (0.56) | KDM4EALDH1A1HPGDMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1961738-A1 | New compounds with antiglutamatergic properties and uses thereof | Faust Pharmaceuticals (FR) | 2008-08-27 | — | — | EP | disclosed |