Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3432599 | 0.87 | ALDH1A1 (0.44) | PTPN1NPC1RAB9AKMT2AMAPT | |
| SCHEMBL3432600 | 0.87 | ALDH1A1 (0.44) | PTPN1NPC1RAB9AKMT2AMAPT | |
| SCHEMBL3253069 | 0.80 | KMT2A (0.50) | KMT2AMAPTRECQLMEN1ALDH1A1 | |
| SCHEMBL14140474 | 0.78 | KMT2A (0.40) | KMT2AMAPTCYP3A4KCNN4MEN1 | |
| SCHEMBL8887284 | 0.77 | MAPT (0.48) | PTPN1KMT2AMAPTCYP1A2CYP3A4 | |
| SCHEMBL8717382 | 0.77 | KMT2A (0.44) | PTPN1NPC1RAB9AKMT2APARP10 | |
| SCHEMBL2294622 | 0.77 | MAPT (0.48) | PTPN1KMT2AMAPTCYP1A2CYP3A4 | |
| SCHEMBL28836942 | 0.76 | KMT2A (0.43) | PTPN1NPC1RAB9AKMT2APARP10 | |
| SCHEMBL15048635 | 0.72 | CES1 (0.50) | NPC1RAB9AKMT2APARP10MAPT | |
| SCHEMBL24361875 | 0.71 | KMT2A (0.47) | PTPN1KMT2AMEN1ALDH1A1CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7414078-B2 | Oral general anesthetics and metabolitically resistant anticonvulsants | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2008-08-19 | — | — | US | disclosed |