SCHEMBL14101261

SCHEMBL14101261

CC(=O)c1cccc(S(=O)(=O)C(Br)(Br)Br)c1

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.56
LMNA P02545 3/20 0.56
KMT2A Q03164 3/20 0.52
SMN1; SMN2 Q16637 4/20 0.47
HTT P42858 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
MAPT P10636 2/20 0.44
POLB P06746 1/20 0.44
ACLY P53396 1/20 0.43
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
CYP19A1 P11511 1/20 0.42
MEN1 O00255 1/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22951476 0.86 ALDH1A1 (0.56) ALDH1A1LMNAKMT2ASMN1; SMN2HTT
SCHEMBL841784 0.84 ALDH1A1 (0.55) ALDH1A1LMNAKMT2ASMN1; SMN2HTT
SCHEMBL7649266 0.84 F2 (0.54) ALDH1A1LMNAKMT2AMAPTCA12
SCHEMBL7650421 0.82 ALDH1A1 (0.42) ALDH1A1LMNAKMT2ASMN1; SMN2HTT
SCHEMBL4216386 0.82 GAA (0.53) ALDH1A1LMNAL3MBTL1MAPTPOLB
SCHEMBL14548240 0.81 HDAC8 (0.53) ALDH1A1LMNAKMT2ASMN1; SMN2HTT
SCHEMBL13656917 0.81 ATM (0.57) ALDH1A1LMNASMN1; SMN2HTTL3MBTL1
SCHEMBL22951477 0.80 ALDH1A1 (0.51) ALDH1A1LMNAKMT2ASMN1; SMN2HTT
SCHEMBL212547 0.79 ALDH1A1 (0.57) ALDH1A1LMNAKMT2ASMN1; SMN2HTT
SCHEMBL4638087 0.79 ALDH1A1 (0.57) ALDH1A1LMNAKMT2ASMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7405744-B2 Thermal developing apparatus FUJFILM CORPORATION (JP) 2008-07-29 US disclosed