Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 7/20 | 0.44 |
| ▸ | DRD4 | P21917 | 7/20 | 0.44 |
| ▸ | TDP2 | O95551 | 3/20 | 0.42 |
| ▸ | NSD2 | O96028 | 3/20 | 0.42 |
| ▸ | APAF1 | O14727 | 3/20 | 0.42 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GALK1 | P51570 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4648774 | 0.89 | DNMT1 (0.46) | DNMT1DRD2DRD4TDP2NSD2 | |
| SCHEMBL4648777 | 0.89 | DNMT1 (0.46) | DNMT1DRD2DRD4TDP2NSD2 | |
| SCHEMBL8171094 | 0.89 | DNMT1 (0.46) | DNMT1DRD2DRD4TDP2NSD2 | |
| SCHEMBL4649480 | 0.75 | APAF1 (0.56) | DNMT1TDP2NSD2APAF1HKDC1 | |
| SCHEMBL4649478 | 0.75 | APAF1 (0.56) | DNMT1TDP2NSD2APAF1HKDC1 | |
| SCHEMBL8170729 | 0.75 | APAF1 (0.56) | DNMT1TDP2NSD2APAF1HKDC1 | |
| SCHEMBL4649553 | 0.72 | DNMT1 (0.83) | DNMT1DRD2DRD4TDP2NSD2 | |
| SCHEMBL9089185 | 0.71 | APAF1 (0.54) | DNMT1TDP2NSD2APAF1HKDC1 | |
| SCHEMBL17249923 | 0.68 | DNMT1 (0.64) | DNMT1DRD2DRD4TDP2NSD2 | |
| SCHEMBL4648986 | 0.64 | IDO1 (0.43) | KMT2AMAPTMAPK1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1961738-A1 | New compounds with antiglutamatergic properties and uses thereof | Faust Pharmaceuticals (FR) | 2008-08-27 | — | — | EP | disclosed |