SCHEMBL14101432

SCHEMBL14101432

c1ccc(-c2ccccc2-c2ccc3ccc4c(-c5ccc6sc7ccc(-c8ccc9ccc%10c(-c%11ccccc%11-c%11ccccc%11)ccc%11ccc8c9c%11%10)cc7c6c5)ccc5ccc2c3c54)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F9 P00740 3/20 0.40
SLC9A1 P19634 2/20 0.36
PIM3 Q86V86 1/20 0.34
S1PR5 Q9H228 7/20 0.34
S1PR4 O95977 6/20 0.34
CHEK1 O14757 1/20 0.34
WEE1 P30291 1/20 0.34
LIMK1 P53667 1/20 0.32
MEN1 O00255 1/20 0.32
APAF1 O14727 1/20 0.32
NPC1 O15118 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
THRB P10828 1/20 0.32
XBP1 P17861 1/20 0.32
PTBP1 P26599 1/20 0.32
HTT P42858 1/20 0.32
RAB9A P51151 1/20 0.32
GALK1 P51570 1/20 0.32
BLM P54132 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14101429 0.94 F9 (0.40) F9SLC9A1PIM3S1PR5S1PR4
SCHEMBL14101532 0.93 F9 (0.42) F9SLC9A1S1PR5S1PR4CHEK1
SCHEMBL14101668 0.93 F9 (0.39) F9SLC9A1PIM3S1PR5S1PR4
SCHEMBL14101430 0.93 F9 (0.39) F9SLC9A1PIM3S1PR5S1PR4
SCHEMBL14101457 0.91 PIM3 (0.41) F9SLC9A1PIM3CHEK1WEE1
SCHEMBL14101667 0.91 PIM3 (0.41) F9SLC9A1PIM3CHEK1WEE1
SCHEMBL14101437 0.90 F9 (0.38) F9SLC9A1PIM3S1PR5S1PR4
SCHEMBL14101575 0.90 F9 (0.38) F9SLC9A1S1PR5S1PR4LIMK1
SCHEMBL14101427 0.90 F9 (0.40) F9SLC9A1PIM3S1PR5S1PR4
SCHEMBL14101670 0.90 F9 (0.40) F9SLC9A1PIM3S1PR5S1PR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080166594-A1 BENZOTHIOPHENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE MAKING USE OF THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2008-07-10 US disclosed
US-20080166594-A1 BENZOTHIOPHENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE MAKING USE OF THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2008-07-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080166594-A1 BENZOTHIOPHENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE MAKING USE OF THE SAME CYBA, BPNT1, TYR F9 3290/4885SLC9A1 1262/4885PIM3 2288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.