SCHEMBL14101527

SCHEMBL14101527

c1ccc(-c2ccc3sc4ccc(-c5ccc6ccc7c(-c8ccc(-c9ccc%10ccccc%10c9)cc8)ccc8ccc5c6c87)cc4c3c2)cc1

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
S1PR5 Q9H228 10/20 0.40
S1PR4 O95977 7/20 0.40
F9 P00740 2/20 0.39
ESR1 P03372 3/20 0.38
ESR2 Q92731 3/20 0.38
GSTP1 P09211 1/20 0.38
PIM3 Q86V86 1/20 0.38
HSD17B1 P14061 2/20 0.37
HSD17B2 P37059 2/20 0.37
LIMK1 P53667 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14101473 0.97 GSTP1 (0.40) S1PR5S1PR4F9ESR1ESR2
SCHEMBL14101463 0.95 S1PR5 (0.40) S1PR5S1PR4F9ESR1ESR2
SCHEMBL14101456 0.95 S1PR5 (0.40) S1PR5S1PR4F9ESR1ESR2
SCHEMBL14101667 0.94 PIM3 (0.41) F9ESR1ESR2PIM3HSD17B1
SCHEMBL14101457 0.94 PIM3 (0.41) F9ESR1ESR2PIM3HSD17B1
SCHEMBL14101530 0.93 S1PR5 (0.39) S1PR5S1PR4ESR1ESR2GSTP1
SCHEMBL14101445 0.93 F9 (0.39) S1PR5S1PR4F9PIM3HSD17B1
SCHEMBL14101535 0.93 ESR1 (0.39) S1PR5S1PR4F9ESR1ESR2
SCHEMBL14101455 0.93 F9 (0.39) S1PR5S1PR4F9PIM3HSD17B1
SCHEMBL14101434 0.93 GSTP1 (0.43) S1PR5S1PR4ESR1ESR2GSTP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080166594-A1 BENZOTHIOPHENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE MAKING USE OF THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2008-07-10 US disclosed
US-20080166594-A1 BENZOTHIOPHENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE MAKING USE OF THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2008-07-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080166594-A1 BENZOTHIOPHENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE MAKING USE OF THE SAME CYBA, BPNT1, TYR S1PR5 4736/4885S1PR4 4464/4885F9 3290/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.