Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.38 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 6/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14101637 | 0.96 | GSTP1 (0.41) | ESR1ESR2CYP1A2ERBB2FYN | |
| SCHEMBL14101589 | 0.94 | CYP1A2 (0.40) | ESR1ESR2CYP1A2ERBB2FYN | |
| SCHEMBL14101644 | 0.93 | HSD17B1 (0.41) | ESR1ESR2CYP1A2ERBB2FYN | |
| SCHEMBL14101639 | 0.93 | CYP1A2 (0.40) | ESR1ESR2CYP1A2ERBB2FYN | |
| SCHEMBL14101590 | 0.93 | CYP1A2 (0.40) | ESR1ESR2CYP1A2ERBB2FYN | |
| SCHEMBL14101605 | 0.93 | CYP1A2 (0.39) | ESR1ESR2CYP1A2ERBB2FYN | |
| SCHEMBL14101607 | 0.91 | CYP1A2 (0.39) | ESR1ESR2CYP1A2ERBB2FYN | |
| SCHEMBL14101633 | 0.91 | ESR1 (0.40) | ESR1ESR2HSD17B1HSD17B2GSTP1 | |
| SCHEMBL14101576 | 0.91 | GSTP1 (0.44) | ESR1ESR2CYP1A2ERBB2FYN | |
| SCHEMBL14101535 | 0.90 | ESR1 (0.39) | ESR1ESR2CYP1A2ERBB2FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080166594-A1 | BENZOTHIOPHENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE MAKING USE OF THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2008-07-10 | — | — | US | disclosed |
| US-20080166594-A1 | BENZOTHIOPHENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE MAKING USE OF THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2008-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080166594-A1 | BENZOTHIOPHENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE MAKING USE OF THE SAME | CYBA, BPNT1, TYR | ESR1 266/4885ESR2 309/4885CYP1A2 232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.