Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.61 |
| ▸ | CA2 | P00918 | 3/20 | 0.61 |
| ▸ | CA7 | P43166 | 3/20 | 0.61 |
| ▸ | CA9 | Q16790 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14369158 | 0.87 | CA1 (0.65) | CA1CA2CA7CA9MEN1 | |
| SCHEMBL573427 | 0.85 | HTT (0.60) | CA1CA2CA7CA9MEN1 | |
| SCHEMBL665917 | 0.85 | MEN1 (0.59) | CA1CA2CA7CA9MEN1 | |
| SCHEMBL26783053 | 0.85 | MEN1 (0.62) | CA1CA2CA7CA9MEN1 | |
| SCHEMBL5551797 | 0.85 | MEN1 (0.62) | CA1CA2CA7CA9MEN1 | |
| SCHEMBL27586589 | 0.85 | MEN1 (0.62) | CA1CA2CA7CA9MEN1 | |
| SCHEMBL7589956 | 0.85 | CA1 (0.65) | CA1CA2CA7CA9MEN1 | |
| SCHEMBL4814264 | 0.83 | MEN1 (0.76) | MEN1KMT2ANPSR1SMN1; SMN2RAB9A | |
| SCHEMBL3970912 | 0.83 | MEN1 (0.76) | MEN1KMT2ANPSR1SMN1; SMN2RAB9A | |
| SCHEMBL7393652 | 0.83 | MEN1 (0.76) | MEN1KMT2ANPSR1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008098056-A2 | HIGH RELAXIVITY CHELATES | EPIX PHARMACEUTICALS, INC. (US) | 2008-08-14 | — | — | WO | disclosed |