SCHEMBL7589956

SCHEMBL7589956

O=C(O)CNC(=O)CN1CCN(C(=O)OCc2ccccc2)CCN(C(=O)OCc2ccccc2)CCN(C(=O)OCc2ccccc2)CC1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.65
CA2 P00918 3/20 0.65
CA7 P43166 3/20 0.65
CA9 Q16790 2/20 0.65
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
NPSR1 Q6W5P4 2/20 0.53
SMN1; SMN2 Q16637 3/20 0.52
NPC1 O15118 2/20 0.52
RAB9A P51151 2/20 0.52
HTT P42858 2/20 0.51
CYP2C19 P33261 1/20 0.50
ALDH1A1 P00352 3/20 0.48
LMNA P02545 1/20 0.48
MAPT P10636 1/20 0.48
USP2 O75604 1/20 0.46
GRIN2B Q13224 2/20 0.46
ADRB1 P08588 1/20 0.45
HRH1 P35367 1/20 0.45
TMEM97 Q5BJF2 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6223335 0.88 CA1 (0.60) CA1CA2CA7CA9MEN1
SCHEMBL14369158 0.88 CA1 (0.65) CA1CA2CA7CA9MEN1
SCHEMBL27586591 0.87 CA1 (0.59) CA1CA2CA7CA9MEN1
SCHEMBL26783053 0.85 MEN1 (0.62) CA1CA2CA7CA9MEN1
SCHEMBL5551797 0.85 MEN1 (0.62) CA1CA2CA7CA9MEN1
SCHEMBL27586589 0.85 MEN1 (0.62) CA1CA2CA7CA9MEN1
SCHEMBL14101795 0.85 CA1 (0.61) CA1CA2CA7CA9MEN1
SCHEMBL8384593 0.84 MEN1 (0.58) CA1CA2CA7CA9MEN1
SCHEMBL13687326 0.84 HTT (0.53) CA1CA2CA7CA9MEN1
SCHEMBL8742079 0.82 MEN1 (0.62) CA1CA2CA7CA9MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1531444-A Synthetic catalyst for selective cleavage of protein and method for selective cleavage of protein using same ������������ʽ���� 2004-09-22 CN disclosed
US-20020165365-A1 Synthetic catalyst for selective cleavage of protein and method for selective cleavage of protein using the same ARTZYME BIOTECH CORPORATION (KR) 2002-11-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020165365-A1 Synthetic catalyst for selective cleavage of protein and method for selective cleavage of protein using the same CPN1, RNPEP, ANPEP CA1 298/4885CA2 1646/4885CA7 1728/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.