Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.55 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.55 |
| ▸ | ITGAV | P06756 | 1/20 | 0.55 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29228688 | 1.00 | ITGB3 (0.55) | ITGB3ITGB1ITGAVITGA5EPHX1 | |
| SCHEMBL17147653 | 0.98 | ITGB3 (0.53) | ITGB3ITGB1ITGAVITGA5EPHX1 | |
| SCHEMBL17138252 | 0.92 | HPGD (0.46) | ITGB3ITGB1ITGAVITGA5EPHX1 | |
| SCHEMBL3457480 | 0.87 | ITGB3 (0.58) | ITGB3ITGB1ITGAVITGA5EPHX1 | |
| Hydrochloric Acid SCHEMBL8843403 | 0.85 | EPHX1 (0.53) | ITGB3ITGB1ITGAVITGA5EPHX1 | |
| SCHEMBL11896375 | 0.85 | HTT (0.43) | ITGB3ITGB1ITGAVITGA5EPHX1 | |
| SCHEMBL19712544 | 0.81 | ITGB3 (0.50) | ITGB3ITGB1ITGAVITGA5EPHX1 | |
| SCHEMBL1410956 | 0.81 | ITGB3 (0.50) | ITGB3ITGB1ITGAVITGA5EPHX1 | |
| SCHEMBL27308454 | 0.81 | ITGB3 (0.49) | ITGB3ITGB1ITGAVITGA5EPHX1 | |
| SCHEMBL7124921 | 0.81 | EPHX2 (0.50) | ITGB3ITGB1ITGAVITGA5EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2295410-A1 | HDAC inhibitor | Chroma Therapeutics Limited (GB) | 2011-03-16 | — | — | EP | disclosed |
| WO-2007082666-A1 | ACYLAMINOIMIDAZOLES | BAYER HEALTHCARE AG (DE) | 2007-07-26 | — | — | WO | disclosed |