Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4998777 | 0.85 | MAPT (0.56) | ERN1MAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL215546 | 0.84 | CYP19A1 (0.54) | ERN1MAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL31597603 | 0.83 | ERN1 (0.62) | ERN1MAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL1098465 | 0.83 | ERN1 (0.62) | ERN1MAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL28825735 | 0.82 | MAPT (0.55) | ERN1MAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL31327257 | 0.82 | MAPT (0.55) | ERN1MAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8164842 | 0.82 | ERN1 (0.53) | ERN1MAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL3997757 | 0.81 | ALDH1A1 (0.60) | ERN1MAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL9824820 | 0.81 | MAPT (0.52) | ERN1MAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL824063 | 0.81 | MAPT (0.52) | ERN1MAPTALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008098056-A2 | HIGH RELAXIVITY CHELATES | EPIX PHARMACEUTICALS, INC. (US) | 2008-08-14 | — | — | WO | disclosed |