Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | CTSC | P53634 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.31 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14101773 | 0.85 | F10 (0.40) | F10F2MAPTMAPK1ALDH1A1 | |
| SCHEMBL4724195 | 0.78 | F10 (0.42) | F10F2MAPTMAPK1ALDH1A1 | |
| SCHEMBL4722495 | 0.78 | F10 (0.44) | F10F2MAPTMAPK1ALDH1A1 | |
| SCHEMBL4724509 | 0.77 | PDE4A (0.41) | F10F2MAPTHTTS1PR1 | |
| SCHEMBL14101715 | 0.77 | AR (0.38) | F10F2MAPTMAPK1ALDH1A1 | |
| SCHEMBL14102004 | 0.76 | F10 (0.37) | F10F2MAPTMAPK1ALDH1A1 | |
| SCHEMBL14101702 | 0.76 | F10 (0.40) | F10F2MAPTMAPK1ALDH1A1 | |
| SCHEMBL14101806 | 0.76 | F10 (0.40) | F10F2MAPTMAPK1ALDH1A1 | |
| SCHEMBL4722822 | 0.76 | F2 (0.37) | F10F2MAPTMAPK1ALDH1A1 | |
| SCHEMBL4724109 | 0.75 | P2RX7 (0.40) | F10F2NOTUMP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |