Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100B | P04271 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | IP6K1 | Q92551 | 2/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL962246 | 0.86 | HTT (0.56) | S100BLMNAHTTMEN1ALDH1A1 | |
| SCHEMBL22169101 | 0.85 | MAPT (0.57) | HTTMEN1ALDH1A1GAAMAPT | |
| SCHEMBL30900463 | 0.85 | MAPT (0.57) | HTTMEN1ALDH1A1GAAMAPT | |
| SCHEMBL2012912 | 0.84 | HTT (0.59) | S100BLMNAHTTMEN1ALDH1A1 | |
| SCHEMBL2053813 | 0.82 | GAA (0.51) | S100BLMNAHTTMEN1ALDH1A1 | |
| SCHEMBL14101966 | 0.79 | AR (0.49) | S100BLMNAHTTMEN1ALDH1A1 | |
| SCHEMBL15117143 | 0.79 | AR (0.49) | S100BLMNAHTTMEN1ALDH1A1 | |
| SCHEMBL2939917 | 0.79 | AR (0.49) | S100BLMNAHTTMEN1ALDH1A1 | |
| SCHEMBL7372826 | 0.77 | MAPT (0.68) | S100BLMNAHTTMEN1ALDH1A1 | |
| SCHEMBL31361984 | 0.77 | MAPT (0.68) | S100BLMNAHTTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |