Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.41 |
| ▸ | TERT | O14746 | 3/20 | 0.41 |
| ▸ | S100B | P04271 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21718932 | 0.82 | MAPT (0.41) | ARLMNAMAPK1HTTTERT | |
| SCHEMBL21718915 | 0.81 | ALDH1A1 (0.42) | LMNAMAPK1HTTSMN1; SMN2PDK2 | |
| SCHEMBL15117143 | 0.79 | AR (0.49) | ARNOTUMLMNAMAPK1HTT | |
| SCHEMBL2939917 | 0.79 | AR (0.49) | ARNOTUMLMNAMAPK1HTT | |
| SCHEMBL14101955 | 0.79 | S100B (0.56) | ARNOTUMLMNAMAPK1HTT | |
| SCHEMBL4723399 | 0.77 | NOTUM (0.48) | ARNOTUM | |
| SCHEMBL4723392 | 0.77 | NOTUM (0.48) | ARNOTUM | |
| SCHEMBL9830003 | 0.77 | TERT (0.48) | LMNAMAPK1HTTSMN1; SMN2TERT | |
| SCHEMBL22043051 | 0.76 | MAPT (0.38) | LMNAMAPK1HTTSMN1; SMN2TERT | |
| SCHEMBL962246 | 0.75 | HTT (0.56) | ARNOTUMLMNAMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |