Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4723280 | 0.76 | ALOX15 (0.34) | PARP1ALOX15SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL14102017 | 0.72 | GRIN2D (0.36) | ATAD2PARP1ALDH1A1MAPTDAO | |
| SCHEMBL918807 | 0.71 | ALOX15 (0.39) | PARP1ALOX15SMN1; SMN2ALDH1A1 | |
| SCHEMBL25697752 | 0.71 | ALOX15 (0.39) | PARP1ALOX15SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL31412446 | 0.70 | NR4A2 (0.42) | PARP1KDM4E | |
| SCHEMBL10037027 | 0.68 | DPYD (0.47) | ALOX15SMN1; SMN2ALDH1A1KDM4ENPSR1 | |
| SCHEMBL14988458 | 0.67 | MAPT (0.56) | ALOX15SMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL7817311 | 0.67 | ALOX15 (0.33) | ATAD2PARP1ALOX15SMN1; SMN2MAPT | |
| SCHEMBL10565952 | 0.66 | SMN1; SMN2 (0.43) | ATAD2PARP1ALOX15SMN1; SMN2ALDH1A1 | |
| SCHEMBL1204138 | 0.66 | SMN1; SMN2 (0.46) | PARP1ALOX15SMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |