Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.41 |
| ▸ | FDPS | P14324 | 9/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13573777 | 1.00 | TSHR (0.47) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL19826869 | 0.97 | TSHR (0.41) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL21185433 | 0.95 | TSHR (0.42) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL19826867 | 0.94 | TSHR (0.39) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL10598536 | 0.89 | TSHR (0.42) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL14429969 | 0.88 | SMPD1 (0.41) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL12671730 | 0.88 | SMPD1 (0.41) | TSHRTHRBGGPS1FDPSSMPD1 | |
| Ammonia Solution, Strong SCHEMBL9391414 | 0.87 | TSHR (0.40) | TSHRTHRBGGPS1FDPSSMPD1 | |
| Ammonia Solution, Strong SCHEMBL829256 | 0.87 | TSHR (0.40) | TSHRTHRBGGPS1FDPSSMPD1 | |
| Ammonia Solution, Strong SCHEMBL324980 | 0.87 | TSHR (0.40) | TSHRTHRBGGPS1FDPSSMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3275867-A1 | CONDENSED RING DERIVATIVE, AND PREPARATION METHOD, INTERMEDIATE, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Shanghai Yingli Pharmaceutical Co. Ltd. (CN) | 2018-01-31 | — | — | EP | disclosed |
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |