Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.37 |
| ▸ | FDPS | P14324 | 9/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL324980 | 1.00 | TSHR (0.40) | TSHRTHRBGGPS1FDPSSMPD1 | |
| Ammonia Solution, Strong SCHEMBL9391414 | 1.00 | TSHR (0.40) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL10598536 | 0.97 | TSHR (0.42) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL13573777 | 0.87 | TSHR (0.47) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL14101975 | 0.87 | TSHR (0.47) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL1958894 | 0.87 | — | — | |
| SCHEMBL19826869 | 0.84 | TSHR (0.41) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL21185433 | 0.82 | TSHR (0.42) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL19826867 | 0.81 | TSHR (0.39) | TSHRTHRBGGPS1FDPSSMPD1 | |
| Ammonia Solution, Strong SCHEMBL8504994 | 0.79 | TSHR (0.44) | TSHRTHRBGGPS1FDPSSMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115572880-B | High-entropy metallocenes, preparation method and application thereof | 华南理工大学 | 2023-06-16 | — | — | CN | claimed |
| US-4745071-A | QUANTITATIVE ANALYSIS FOR LEUKOCYTES | SEQUOIA-TURNER CORPORATION (US) | 1988-05-17 | — | — | US | claimed |
| CN-112500847-B | Cadmium ion probe based on quantum dot fluorescence resonance energy transfer system and preparation method thereof | 武汉理工大学 | 2023-07-18 | — | — | CN | disclosed |
| CN-115572880-B | High-entropy metallocenes, preparation method and application thereof | 华南理工大学 | 2023-06-16 | — | — | CN | disclosed |
| US-8304243-B2 | Reagents and methods for classifying leukocytes | SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD. (CN) | 2012-11-06 | — | — | US | disclosed |
| US-20120183992-A1 | Reagents and Methods for Classifying Leukocytes | SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD. (CN) | 2012-07-19 | — | — | US | disclosed |
| US-8143064-B2 | Reagents and methods for classifying leukocytes | SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD. (CN) | 2012-03-27 | — | — | US | disclosed |
| US-20090162830-A1 | REAGENTS AND METHODS FOR CLASSIFYING LEUKOCYTES | SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD. (CN) | 2009-06-25 | — | — | US | disclosed |
| US-5250438-A | Controls white cell shrinkage | STRECK LABORATORIES, INC. (US) | 1993-10-05 | — | — | US | disclosed |
| US-5045474-A | Semi-automatic process for white cell differential count | SEQUOIA-TURNER CORPORATION (UNIPATH) (US) | 1991-09-03 | — | — | US | disclosed |
| US-4745071-A | QUANTITATIVE ANALYSIS FOR LEUKOCYTES | SEQUOIA-TURNER CORPORATION (US) | 1988-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090162830-A1 | REAGENTS AND METHODS FOR CLASSIFYING LEUKOCYTES | CD14, CD47, HCLS1 | TSHR 3094/4885THRB 3973/4885GGPS1 4505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.