Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14046299 | 0.88 | MTTP (0.71) | MTTP | |
| SCHEMBL14027799 | 0.84 | MTTP (0.69) | MTTP | |
| SCHEMBL4940917 | 0.81 | MTTP (0.72) | MTTP | |
| SCHEMBL1621570 | 0.79 | MTTP (1.00) | MTTP | |
| SCHEMBL4784321 | 0.78 | MTTP (0.70) | MTTP | |
| SCHEMBL4744467 | 0.78 | MTTP (0.74) | MTTP | |
| SCHEMBL14027838 | 0.78 | MTTP (0.74) | MTTP | |
| SCHEMBL4784881 | 0.78 | MTTP (0.67) | MTTP | |
| SCHEMBL4784880 | 0.78 | MTTP (0.67) | MTTP | |
| Hydrochloric Acid SCHEMBL4939216 | 0.77 | MTTP (0.73) | MTTP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008100423-A1 | GUT MICROSOMAL TRIGLYCERIDE TRANSPORT PROTEIN INHIBITORS | SIRTRIS PHARMACEUTICALS, INC. (US) | 2008-08-21 | — | — | WO | disclosed |