SCHEMBL1621570

SCHEMBL1621570

CC(C)(C)c1ccc(-c2ccccc2C(=O)Nc2ccc3cc(C(=O)N[C@H](C(=O)NCc4ccc(F)cc4)c4ccccc4)ccc3n2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ MTTP P55157 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13993530 0.87 MTTP (1.00) MTTP
SCHEMBL1622842 0.87 MTTP (1.00) MTTP
SCHEMBL14186885 0.82 MTTP (0.70) MTTP
SCHEMBL1600315 0.82 MTTP (0.70) MTTP
SCHEMBL14132458 0.81 MTTP (0.68) MTTP
SCHEMBL14046302 0.81 MTTP (0.68) MTTP
SCHEMBL3232241 0.79 MTTP (0.84) MTTP
SCHEMBL13495432 0.79 MTTP (0.84) MTTP
SCHEMBL14102295 0.79 MTTP (0.66) MTTP
SCHEMBL3175315 0.79 MTTP (0.73) MTTP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7935342-B2 Methods for treating obesity by administering a trkB antagonist RINAT NEUROSCIENCE CORP. (US) 2011-05-03 — — US disclosed
US-7928099-B2 Pyrimido [4,5-D] azepine derivatives as 5-HT2c agonists PFIZER INC (US) 2011-04-19 — — US disclosed
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