Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16957647 | 0.90 | SLC7A5 (0.52) | SLC7A5HSD17B10CA12CA1CA2 | |
| SCHEMBL2319081 | 0.90 | CA12 (0.61) | SLC7A5HSD17B10CA12CA1CA2 | |
| SCHEMBL16956660 | 0.90 | SLC7A5 (0.68) | SLC7A5HSD17B10CA12CA1CA2 | |
| SCHEMBL27387791 | 0.88 | SLC7A5 (0.48) | SLC7A5HSD17B10CA12CA1CA2 | |
| SCHEMBL16956657 | 0.88 | SLC7A5 (0.48) | SLC7A5HSD17B10CA12CA1CA2 | |
| SCHEMBL16957645 | 0.85 | SLC7A5 (0.46) | SLC7A5HSD17B10CA12CA1CA2 | |
| SCHEMBL16958657 | 0.84 | SLC7A5 (0.45) | SLC7A5HSD17B10CA12CA1CA2 | |
| SCHEMBL16958660 | 0.84 | SLC7A5 (0.45) | SLC7A5HSD17B10CA12CA1CA2 | |
| SCHEMBL1790854 | 0.82 | SLC7A5 (0.68) | SLC7A5KDM4ELOXL2CYP4F2CYP4A11 | |
| SCHEMBL17046379 | 0.81 | LOXL2 (0.44) | SLC7A5HSD17B10CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1695705-B1 | Compounds effecting glucokinase | ASTRAZENECA AB (SE) | 2008-08-06 | — | — | EP | disclosed |