Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 2/20 | 0.57 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.57 |
| ▸ | SMO | Q99835 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8908188 | 0.88 | MAPT (0.62) | CSNK1DMAPK14SMOMAPTNPSR1 | |
| SCHEMBL1753096 | 0.87 | CSNK1D (0.54) | CSNK1DMAPK14SMOMAPTNPSR1 | |
| SCHEMBL12706599 | 0.83 | CSNK1D (0.54) | CSNK1DMAPK14MAPTNPSR1LMNA | |
| SCHEMBL14102661 | 0.80 | SMO (0.40) | CSNK1DMAPK14SMOMAPTNPSR1 | |
| Tt-301 SCHEMBL529969 | 0.73 | CSNK1D (0.60) | CSNK1DMAPK14MAPTNPSR1LMNA | |
| SCHEMBL1753099 | 0.73 | CSNK1D (0.60) | CSNK1DMAPK14MAPTNPSR1LMNA | |
| Tt-301 SCHEMBL529453 | 0.72 | CSNK1D (0.59) | CSNK1DMAPK14MAPTNPSR1LMNA | |
| SCHEMBL1752939 | 0.72 | MAPK14 (1.00) | CSNK1DMAPK14MAPTNPSR1LMNA | |
| Tt-301 SCHEMBL9998818 | 0.72 | CSNK1D (0.59) | CSNK1DMAPK14MAPTNPSR1LMNA | |
| SCHEMBL1753135 | 0.72 | MAPK14 (1.00) | CSNK1DMAPK14MAPTNPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008094208-A2 | PROTEIN KINASE TARGETED THERAPEUTICS | NORTHWESTERN UNIVERSITY (US) | 2008-08-07 | — | — | WO | disclosed |