Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.59 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.56 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.56 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.56 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.56 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.56 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.53 |
| ▸ | FAAH | O00519 | 4/20 | 0.53 |
| ▸ | CHRND | Q07001 | 3/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14102642 | 1.00 | EPHX2 (0.59) | EPHX2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL14102844 | 1.00 | EPHX2 (0.59) | EPHX2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL12148893 | 0.91 | GRIA1 (0.66) | GRIA1CHRND | |
| SCHEMBL9519035 | 0.89 | CHRNB2 (0.69) | CHRNB2CHRNB4CHRNA3CHRNA4GRIA1 | |
| SCHEMBL6438848 | 0.89 | CHRNB2 (0.69) | CHRNB2CHRNB4CHRNA3CHRNA4GRIA1 | |
| SCHEMBL12324830 | 0.86 | CHRNB2 (0.69) | CHRNB2CHRNB4CHRNA3CHRNA4GRIA1 | |
| SCHEMBL16247369 | 0.86 | CHRNB2 (0.69) | CHRNB2CHRNB4CHRNA3CHRNA4GRIA1 | |
| SCHEMBL14103239 | 0.86 | EPHX2 (0.49) | EPHX2GRIA1PSMB5FAAH | |
| SCHEMBL14102636 | 0.86 | EPHX2 (0.49) | EPHX2GRIA1PSMB5FAAH | |
| SCHEMBL14102639 | 0.86 | EPHX2 (0.49) | EPHX2GRIA1PSMB5FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008102127-A2 | GEL FORMING COMPOUNDS | PLIVA HRVATSKA D.O.O. (HR) | 2008-08-28 | — | — | WO | disclosed |