Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.43 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.43 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4772055 | 0.99 | HPGDS (0.44) | LMNARXFP1HPGDSBMPR1BBMPR1A | |
| Hydrochloric Acid SCHEMBL4793876 | 0.98 | HPGDS (0.43) | LMNARXFP1HPGDSBMPR1BBMPR1A | |
| SCHEMBL4769788 | 0.86 | PTK2 (0.39) | RXFP1POLBMAPTRAB9ANPC1 | |
| SCHEMBL4766720 | 0.85 | PRKD1 (0.41) | LMNATP53POLBMAPTHPGD | |
| SCHEMBL4763700 | 0.85 | KDM2B (0.39) | LMNARXFP1MAPTRAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL6289277 | 0.85 | PTK2 (0.39) | RXFP1POLBMAPTRAB9ANPC1 | |
| SCHEMBL4763442 | 0.85 | AURKA (0.40) | RXFP1TGFBR1TP53 | |
| Hydrochloric Acid SCHEMBL4763531 | 0.85 | PRKD1 (0.41) | LMNATP53POLBMAPTHPGD | |
| Hydrochloric Acid SCHEMBL4774011 | 0.84 | AURKA (0.40) | RXFP1TGFBR1TP53 | |
| SCHEMBL6289169 | 0.84 | PIK3CA (0.41) | LMNATP53POLBMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020445-B1 | FUSED PYRIDINE DERIVATIVES | EISAI R&D MAN CO LTD (JP) | 2008-08-13 | — | — | EP | disclosed |