Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.46 |
| ▸ | NPY1R | P25929 | 3/20 | 0.44 |
| ▸ | NPY4R | P50391 | 3/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14103239 | 0.89 | EPHX2 (0.49) | LMNAMAPTMAPK1EPHX2MMP9 | |
| SCHEMBL14102634 | 0.89 | CAPN1 (0.49) | LMNAMAPTMAPK1EPHX2MMP9 | |
| SCHEMBL14102639 | 0.89 | EPHX2 (0.49) | LMNAMAPTMAPK1EPHX2MMP9 | |
| SCHEMBL14102636 | 0.89 | EPHX2 (0.49) | LMNAMAPTMAPK1EPHX2MMP9 | |
| SCHEMBL14103244 | 0.83 | EPHX2 (0.53) | EPHX2NPY1RFAAH | |
| SCHEMBL18328442 | 0.78 | EPHX2 (0.72) | MAPTEPHX2TRPV1FAAHALDH1A1 | |
| SCHEMBL14102773 | 0.78 | EPHX2 (0.72) | MAPTEPHX2TRPV1FAAHALDH1A1 | |
| SCHEMBL12980257 | 0.78 | EPHX2 (0.72) | MAPTEPHX2TRPV1FAAHALDH1A1 | |
| SCHEMBL14102597 | 0.78 | SIRT2 (0.47) | EPHX2 | |
| SCHEMBL14102771 | 0.77 | EPHX2 (0.53) | LMNAMAPTMAPK1EPHX2TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008102127-A2 | GEL FORMING COMPOUNDS | PLIVA HRVATSKA D.O.O. (HR) | 2008-08-28 | — | — | WO | disclosed |