Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | G6PD | P11413 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12417059 | 0.88 | KMT2A (0.58) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL12417062 | 0.83 | KMT2A (0.67) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL12417065 | 0.82 | KMT2A (0.58) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL12417068 | 0.81 | MEN1 (0.56) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL12417025 | 0.75 | ALDH1A1 (0.57) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL12417037 | 0.75 | KDM4E (0.57) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL12417054 | 0.74 | ALDH1A1 (0.51) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL12417046 | 0.73 | ALDH1A1 (0.55) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL12417030 | 0.73 | ALDH1A1 (0.50) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL12417031 | 0.72 | KDM4E (0.57) | KMT2AMEN1ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008094319-A2 | METHODS AND COMPOSITIONS OF TRAIL-DEATH RECEPTOR AGONISTS/ACTIVATORS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYTEM (US) | 2008-08-07 | — | — | WO | disclosed |