Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 11/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | GAA | P10253 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | PIKFYVE | Q9Y2I7 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 5/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TEX264 | Q9Y6I9 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14103591 | 0.93 | MAPT (0.51) | LMNAHTTMAPTKMT2AGAA | |
| SCHEMBL14104222 | 0.78 | MAPT (0.48) | LMNAHTTMAPTKMT2AGAA | |
| SCHEMBL12417173 | 0.78 | MAPT (0.56) | LMNAHTTMAPTKMT2AGAA | |
| SCHEMBL11913670 | 0.74 | MAPT (0.58) | LMNAHTTMAPTKMT2AGAA | |
| SCHEMBL22737807 | 0.72 | MAPT (0.68) | LMNAHTTMAPTKMT2AGAA | |
| SCHEMBL29345146 | 0.71 | LMNA (0.94) | LMNAHTTMAPTKMT2AGAA | |
| SCHEMBL12417175 | 0.71 | MAPT (0.61) | LMNAHTTMAPTKMT2AGAA | |
| SCHEMBL12829050 | 0.70 | MAPT (0.54) | LMNAHTTMAPTKMT2AGAA | |
| SCHEMBL22737384 | 0.69 | MAPT (0.70) | LMNAHTTMAPTKMT2AGAA | |
| SCHEMBL11810697 | 0.69 | LMNA (1.00) | LMNAHTTMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008094319-A2 | METHODS AND COMPOSITIONS OF TRAIL-DEATH RECEPTOR AGONISTS/ACTIVATORS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYTEM (US) | 2008-08-07 | — | — | WO | disclosed |