Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7541540 | 0.91 | MEN1 (0.35) | MEN1KMT2ABACE1ESR1AR | |
| SCHEMBL13054967 | 0.91 | MEN1 (0.35) | MEN1KMT2ABACE1ESR1AR | |
| SCHEMBL13054594 | 0.88 | ABCC9 (0.35) | MEN1KMT2AESR1 | |
| SCHEMBL13081820 | 0.88 | MEN1 (0.34) | MEN1KMT2AESR1 | |
| SCHEMBL7566880 | 0.88 | ABCC9 (0.35) | MEN1KMT2AESR1 | |
| SCHEMBL7572424 | 0.85 | AR (0.37) | MEN1KMT2AAR | |
| SCHEMBL13054170 | 0.85 | AR (0.37) | MEN1KMT2AAR | |
| SCHEMBL13054488 | 0.85 | MEN1 (0.37) | MEN1KMT2ATACR1ESR1 | |
| SCHEMBL7585732 | 0.85 | MEN1 (0.37) | MEN1KMT2ATACR1ESR1 | |
| SCHEMBL13054304 | 0.84 | BACE1 (0.30) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008103351-A2 | HETEROCYCLIC ASPARTYL PROTEASE INHIBITORS | SCHERING CORPORATION (US) | 2008-08-28 | — | — | WO | disclosed |