ABCC9 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL482507	0.59	20/20
SCHEMBL482218	1.00	19/20
SCHEMBL482223	1.00	19/20
SCHEMBL482334	1.00	19/20
SCHEMBL482326	0.86	19/20
SCHEMBL481830	1.00	18/20
SCHEMBL482180	1.00	18/20
SCHEMBL481905	0.66	18/20
SCHEMBL482172	1.00	17/20
SCHEMBL482208	1.00	17/20
SCHEMBL482567	1.00	17/20
SCHEMBL482228	0.86	17/20
SCHEMBL482493	0.83	17/20
SCHEMBL482446	0.78	17/20
SCHEMBL482913	0.78	17/20
SCHEMBL482432	0.69	17/20
SCHEMBL482280	0.68	17/20
SCHEMBL482360	0.67	17/20
SCHEMBL482499	0.64	17/20
SCHEMBL482335	0.64	17/20

Clinical trials — most relevant to ABCC9 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Sulphonylurea Receptor Mutation and Responsiveness to Gliclazide - a Pilot Proof of Concept, Randomised Cross-over Study	PHASE4	COMPLETED
Study of the Long-term Effects of P2Y12 Inhibitor Monotherapy and Coagulation Markers After Percutaneous Coronary Angioplasty.	PHASE3	RECRUITING
A Phase 2 Trial of SCO-101 in Combination With FOLFIRI for Patients With Metastatic Colorectal Cancer (mCRC) With Acquired Resistance to FOLFIRI	PHASE1/PHASE2	UNKNOWN
A Phase II Study of ABC294640 as Monotherapy in Patients With Advanced Hepatocellular Carcinoma	PHASE2	WITHDRAWN
Surgery Plus Chemotherapy (Doxorubicin, Vincristine and Etoposide), Mitotane, and Tariquidar to Treat Adrenocortical Cancer	PHASE2	COMPLETED
Clofarabine and Cytarabine in Treating Young Patients With Refractory or Relapsed Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia	PHASE1/PHASE2	COMPLETED
Influence of Ethnicity and ABCB1 Gene Polymorphism on the Pharmacokinetics of Azithromycin in Healthy Bangladeshi Volunteers	PHASE1	UNKNOWN
Veliparib and Irinotecan Hydrochloride in Treating Patients With Cancer That Is Metastatic or Cannot Be Removed by Surgery	PHASE1	COMPLETED
Indenoisoquinoline LMP744 in Adults With Relapsed Solid Tumors and Lymphomas	PHASE1	COMPLETED
Effect of, OAT3, on the Renal Secretion of Cefotaxime	PHASE1	COMPLETED
Pharmacokinetic Drug-Drug Interaction Study to Identify Biomarkers of Kidney Transporters	EARLY_PHASE1	COMPLETED
Multidrug Resistance Genes in Patients With Acute Myeloid Leukemia	nan	ACTIVE_NOT_RECRUITING
Bile Acids Metabolism and Genetic Mutation Profile in the Intrahepatic Cholestasis of Pregnacy in Indian Population	nan	RECRUITING
the Effect of ABCC2 Genetic Polymorphism on Neurotoxicity in Gastrointestinal Cancer Patients Receiving Oxaliplatin	nan	UNKNOWN
Coproporphyrine Isomers and Methotrexate Elimination	nan	COMPLETED
Placental Transfer of Tenofovir	nan	COMPLETED
Natural History Study of ATP1A3-related Disease	nan	UNKNOWN
Prescreening Study to Identify Potential Wilson Disease Participants for Gene-Editing Clinical Trial	nan	ACTIVE_NOT_RECRUITING
Metformin Reduce the Relapse Rate on Patients With B-cell Precursor (Ph+ Negative) Acute Lymphoblastic Leukemia	nan	COMPLETED
Role of the ATP7A Transporter in Ovarian Cancer	nan	COMPLETED
Collection of Tissue Samples for Study of Multidrug Resistance	nan	COMPLETED
Impact of Genetics on Metformin Pharmacokinetics	nan	COMPLETED
Role of Sorcin and Annexin A3 in Breast Cancer Patients	nan	UNKNOWN
Genetic Study for Infantile Onset Diabetes Mellitus	nan	UNKNOWN
Pharmacogenetics Study in Taiwan's Ethnic Groups	nan	COMPLETED
Pharmacogenomics of New Antiretrovirals	nan	COMPLETED
Effect of Metformin on ABCB1 and AMPK Expression in Adolescents With Newly Diagnosed Acute Lymphoblastic Leukemia	nan	UNKNOWN
An Observational Study in Children and Adults With Stargardt Disease	nan	ACTIVE_NOT_RECRUITING
Impact of Sulphonylureas on Neurodevelopmental Outcomes in KCNJ11-related Intermediate Developmental Delay, Epilepsy and Neonatal Diabetes (iDEND) Syndrome	nan	RECRUITING
Hydroxychloroquin (HCQ) in chILD of Genetic Defect	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a ABCC9 binder may also engage these)

Protein	Name	Similarity
P82451	—	1.000	P82451 →
Q63563	—	1.000	Q63563 →
Q09429	—	1.000	Q09429 →
ABCC8	ATP-binding cassette sub-family C member 8	1.000	landscape →
P70170	—	1.000	P70170 →
Q09427	—	1.000	Q09427 →
P26361	—	0.996	P26361 →
Q63120	—	0.996	Q63120 →
Q2QLB4	—	0.996	Q2QLB4 →
Q00555	—	0.996	Q00555 →
P39109	—	0.995	P39109 →
Q2QLE5	—	0.995	Q2QLE5 →
Q9QYM0	—	0.995	Q9QYM0 →
Q00PJ2	—	0.994	Q00PJ2 →
Q00554	—	0.994	Q00554 →
Q9U2G5	—	0.994	Q9U2G5 →
Q9R1X5	—	0.994	Q9R1X5 →
P26362	—	0.994	P26362 →
Q96J66	—	0.994	Q96J66 →
P35071	—	0.994	P35071 →
Q2IBF6	—	0.994	Q2IBF6 →
Q2QLA3	—	0.994	Q2QLA3 →
Q07DX5	—	0.994	Q07DX5 →
Q09YK5	—	0.994	Q09YK5 →
Q7JII8	—	0.994	Q7JII8 →
Q9TUQ2	—	0.994	Q9TUQ2 →
Q9M1C7	—	0.994	Q9M1C7 →
Q07DY5	—	0.993	Q07DY5 →
Q9TSP5	—	0.993	Q9TSP5 →
Q108U0	—	0.993	Q108U0 →