Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14105802 | 0.86 | BRD4 (0.36) | BRD4BACE1 | |
| SCHEMBL7552846 | 0.86 | PLA2G7 (0.38) | BACE1 | |
| SCHEMBL13081679 | 0.80 | BRD4 (0.36) | BRD4 | |
| SCHEMBL7541545 | 0.80 | BACE1 (0.44) | BRD4CTSDBACE1 | |
| SCHEMBL14105260 | 0.80 | TRIM24 (0.35) | BRD4BACE1 | |
| SCHEMBL13081787 | 0.80 | BRD4 (0.36) | BRD4 | |
| SCHEMBL13081556 | 0.79 | BRD4 (0.35) | BRD4 | |
| SCHEMBL14105226 | 0.79 | BRD4 (0.34) | BRD4 | |
| SCHEMBL4559930 | 0.78 | CYP2A6 (0.33) | BRD4BACE1 | |
| SCHEMBL14105704 | 0.78 | BRD4 (0.34) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008103351-A2 | HETEROCYCLIC ASPARTYL PROTEASE INHIBITORS | SCHERING CORPORATION (US) | 2008-08-28 | — | — | WO | disclosed |