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Sugi Predict / Targets / PLA2G7

PLA2G7

Platelet-activating factor acetylhydrolase · Q13093 · PLA2G7 on Sugi Atlas →

29,517 patent compounds predicted against PLA2G7, 15,925 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL490530 SCHEMBL490530 0.55 14/20
SCHEMBL874239 SCHEMBL874239 0.62 12/20
SCHEMBL876057 SCHEMBL876057 0.54 11/20
SCHEMBL877316 SCHEMBL877316 0.63 10/20
SCHEMBL876881 SCHEMBL876881 0.58 10/20
SCHEMBL875311 SCHEMBL875311 0.58 10/20
SCHEMBL875787 SCHEMBL875787 0.55 10/20
SCHEMBL875805 SCHEMBL875805 0.55 10/20
SCHEMBL878256 SCHEMBL878256 0.64 9/20
SCHEMBL875634 SCHEMBL875634 0.58 9/20
SCHEMBL875646 SCHEMBL875646 0.56 9/20
SCHEMBL365662 SCHEMBL365662 0.46 8/20
SCHEMBL878045 SCHEMBL878045 0.46 8/20
SCHEMBL875588 SCHEMBL875588 0.45 8/20
SCHEMBL875480 SCHEMBL875480 0.41 8/20
SCHEMBL312027 SCHEMBL312027 0.47 7/20
SCHEMBL875734 SCHEMBL875734 0.43 7/20
SCHEMBL734681 SCHEMBL734681 0.67 6/20
SCHEMBL734682 SCHEMBL734682 0.67 6/20
SCHEMBL841078 SCHEMBL841078 0.61 6/20

Clinical trials — most relevant to PLA2G7 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Determining Genetic Role in Treatment Response to Anti-Platelet Interventions (The PAPI Study) PHASE4COMPLETED
Eicosapentaenoic Acid Cerebral Vasospasm Therapy Study PHASE4COMPLETED
Pharmacogenomics of Antiplatelet Response - I PHASE4COMPLETED
Pharmacogenomics of Antiplatelet Response PHASE4COMPLETED
Atorvastatin, Aspirin, Oxidative Stress, Coagulation and Platelet Activation Indexes PHASE4UNKNOWN
Comparison of Simvastatin Versus Simvastatin/Ezetimibe on Small Dense Low -Density Lipoprotein (LDL) PHASE4COMPLETED
Aspirin and Renal Disease Progression in Patients With Type 2 Diabetes PHASE3UNKNOWN
Efficacy and Safety of Carica Papaya in Dengue Fever: A Randomised Clinical Trial PHASE3COMPLETED
Combined Treatment of Methotrexate + Glucocorticoids Versus Glucocorticoids Alone in Patients With PM and DM PHASE3COMPLETED
Fish Oil and Aspirin With Type 2 Diabetes PHASE2COMPLETED
Lovaza's Effect on the Activation of Platelets PHASE2COMPLETED
Effect of Gemfibrozil on Serum Glycosylphosphatidylinositol (GPI) Phospholipase D and Triglycerides PHASE1COMPLETED
Assessment of Coronary Plaque Composition PHASE1COMPLETED
The Impact of Genotype on Pharmacokinetics and Antiplatelet Effects of Ticagrelor in Healthy Chinese PHASE1COMPLETED
SB-659032 Platelet Aggregation Study PHASE1COMPLETED
Physiopathology of Pulmonary Arterial Hypertension: Mechanistic Studies nanUNKNOWN
PLatelets Acetyl-CoA Carboxylase Phosphorylation State in SEPtic Shock nanCOMPLETED
EPICO: (Study for the Pro-resolution of Chronic Inflammation in Obesity. Original Acronym From Spanish) nanUNKNOWN
The Association Between Post-ERCP Acute Pancreatitis and Various Genetic Mutations nanCOMPLETED
Genetic Markers of CHD Risk in Men and Women nanCOMPLETED
Validation of an Assay to Measure Cyclooxygenase-1 Activity nanCOMPLETED
Platelets Function and Cardiovascular Events in Patients With End Stage Renal Disease nanUNKNOWN
Role of Anti-mouse PLA2R1 ELISA in Membranous Nephropathy nanCOMPLETED
Hypolipemic Treatment in Acute Coronary Syndrome (ACS): Antithrombotic Effects nanUNKNOWN
Platelet Hyperreactivity Project nanCOMPLETED
Positron Emission Tomography (PET) to Study Brain Signaling nanCOMPLETED
Platelet-activating Factor Acetylhydrolase (Paf-ah) Gene Expression nanCOMPLETED
In Vitro Demonstration of Direct Platelet-Related Effects of PCSK9 Enzyme nanNOT_YET_RECRUITING
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) nanCOMPLETED
Plasma Free Fatty Acids Profile As A Diagnostic Tool For Acute Ischemic Stroke nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a PLA2G7 binder may also engage these)

ProteinNameSimilarity
Q60963 — 1.000 Q60963 →
Q28262 — 0.999 Q28262 →
Q28017 — 0.997 Q28017 →
P70683 — 0.994 P70683 →
Q8VDG7 — 0.986 Q8VDG7 →
P83006 — 0.984 P83006 →
Q95K79 — 0.982 Q95K79 →
Q96BT7 — 0.982 Q96BT7 →
Q3U213 — 0.982 Q3U213 →
Q90678 — 0.982 Q90678 →
Q0P5B7 — 0.981 Q0P5B7 →
Q5SNQ7 — 0.981 Q5SNQ7 →
Q5XHF8 — 0.981 Q5XHF8 →
Q5ZKL5 — 0.980 Q5ZKL5 →
Q80Y20 — 0.980 Q80Y20 →
Q8C0L9 — 0.980 Q8C0L9 →
Q6GLL2 — 0.979 Q6GLL2 →
Q3MHZ7 — 0.979 Q3MHZ7 →
ABHD5 1-acylglycerol-3-phosphate O-acyltransferase 0.979 landscape →
PRMT9 Protein arginine N-methyltransferase 9 0.979 landscape →
Q4KLT3 — 0.979 Q4KLT3 →
Q6NTR1 — 0.979 Q6NTR1 →
Q9CQF9 — 0.979 Q9CQF9 →
Q9Z2A8 — 0.979 Q9Z2A8 →
Q8BTI9 — 0.979 Q8BTI9 →
MBTPS1 Membrane-bound transcription factor site-1 protease 0.978 landscape →
Q802V6 — 0.978 Q802V6 →
Q5NDE7 — 0.978 Q5NDE7 →
Q5PPS7 — 0.978 Q5PPS7 →
Q5K651 — 0.978 Q5K651 →