Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 20/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14107491 | 0.91 | CCR2 (0.42) | CCR2 | |
| SCHEMBL4872156 | 0.81 | NQO2 (0.39) | — | |
| SCHEMBL4864493 | 0.70 | NQO2 (0.40) | — | |
| SCHEMBL14169378 | 0.69 | CCR2 (0.70) | CCR2 | |
| SCHEMBL4867741 | 0.68 | TAAR1 (0.35) | — | |
| SCHEMBL4792743 | 0.68 | MAPT (0.33) | — | |
| SCHEMBL13691503 | 0.67 | CCR2 (0.51) | CCR2 | |
| SCHEMBL14169662 | 0.67 | CCR2 (0.63) | CCR2 | |
| SCHEMBL14513598 | 0.66 | CCR2 (0.52) | CCR2 | |
| SCHEMBL4792692 | 0.66 | BACE1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7393844-B2 | Tetrahydropyranyl cyclopentyl heterocyclic amide modulators of chemokine receptor activity | MERCK & CO., INC. (US) | 2008-07-01 | — | — | US | disclosed |