Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 16/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14107928 | 0.92 | VDR (0.54) | VDRHDAC3HDAC2HDAC6 | |
| SCHEMBL14107933 | 0.89 | VDR (0.46) | VDR | |
| SCHEMBL14107931 | 0.86 | VDR (0.49) | VDR | |
| SCHEMBL14107927 | 0.84 | VDR (0.50) | VDR | |
| SCHEMBL14153952 | 0.80 | VDR (0.56) | VDRHDAC3HDAC2HDAC6 | |
| SCHEMBL14107897 | 0.79 | VDR (0.48) | VDRHDAC3HDAC2HDAC6 | |
| SCHEMBL14153928 | 0.79 | VDR (0.52) | VDRHDAC3HDAC2HDAC6 | |
| SCHEMBL14107929 | 0.79 | VDR (0.70) | VDRHDAC3HDAC2HDAC6 | |
| SCHEMBL14107846 | 0.78 | VDR (0.72) | VDR | |
| SCHEMBL14107906 | 0.78 | VDR (0.54) | VDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7402688-B2 | 2,2-Di-substituted 1alpha,25-dihydroxy-19-norvitamin D derivative | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-07-22 | — | — | US | disclosed |