Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 14/20 | 0.38 |
| ▸ | BCHE | P06276 | 12/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | MARK4 | Q96L34 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14108561 | 0.94 | SLC22A1 (0.43) | SLC22A1OPRM1ACHEBCHESLC6A2 | |
| SCHEMBL14108644 | 0.92 | SLC22A1 (0.42) | SLC22A1OPRM1ACHEBCHESLC6A2 | |
| SCHEMBL14108578 | 0.91 | SLC22A1 (0.43) | SLC22A1OPRM1ACHEBCHESLC6A2 | |
| SCHEMBL14108562 | 0.90 | SLC22A1 (0.39) | SLC22A1OPRM1ACHEBCHESLC6A2 | |
| SCHEMBL1746077 | 0.89 | SLC22A1 (0.42) | SLC22A1OPRM1ACHEBCHESLC6A2 | |
| SCHEMBL14108556 | 0.89 | SLC22A1 (0.41) | SLC22A1OPRM1ACHEBCHESLC6A2 | |
| SCHEMBL14127021 | 0.86 | ACHE (0.39) | ACHEBCHESLC6A2SLC6A4TP53 | |
| SCHEMBL12047316 | 0.82 | SLC22A1 (0.47) | SLC22A1OPRM1ACHEBCHESLC6A2 | |
| SCHEMBL10031276 | 0.82 | SLC22A1 (0.47) | SLC22A1OPRM1ACHEBCHESLC6A2 | |
| SCHEMBL14127399 | 0.80 | ACHE (0.39) | ACHEBCHESLC6A2SLC6A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012164055-A2 | NEW COMPOUNDS, SYNTHESIS AND USE THEREOF IN THE TREATMENT OF PAIN | LACER, S.A. (ES) | 2012-12-06 | — | — | WO | disclosed |
| EP-2530072-A1 | New compounds, synthesis and use thereof in the treatment of pain | LACER, S.A. (ES) | 2012-12-05 | — | — | EP | disclosed |