Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 5/20 | 0.49 |
| ▸ | KCNA2 | P16389 | 1/20 | 0.47 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.47 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6014056 | 0.87 | MAPT (0.48) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| Hydrochloric Acid SCHEMBL891074 | 0.86 | MAPT (0.47) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL3504340 | 0.81 | MAPT (0.54) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL4947232 | 0.80 | MAOB (0.61) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL9741291 | 0.80 | PRKCI (0.55) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL1728168 | 0.78 | MAOB (0.76) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL30892463 | 0.78 | MAOB (0.76) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL1559781 | 0.77 | MAPT (0.72) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| Acetic Acid SCHEMBL9653704 | 0.77 | SMN1; SMN2 (0.52) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL2009073 | 0.75 | CREBBP (0.66) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7399789-B2 | Drug delivering agents is chemically bonded to a bone active agent; for treatment of bone injury, bone metabolic disorders, prophylaxis or diagnosis; targeting to bone | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION (US) | 2008-07-15 | — | — | US | disclosed |