Sugi Predict

Sugi Predict / Compounds / SCHEMBL2009073

SCHEMBL2009073

SCHEMBL2009073

CC(=O)c1ccc(OCc2ccccc2)c(N)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CREBBP Q92793 1/20 0.66
▸ MAOB P27338 2/20 0.59
▸ MRGPRX4 Q96LA9 1/20 0.55
▸ SMN1; SMN2 Q16637 4/20 0.52
▸ NPC1 O15118 2/20 0.52
▸ RAB9A P51151 2/20 0.52
▸ HPGD P15428 1/20 0.52
▸ USP2 O75604 1/20 0.51
▸ HSD17B10 Q99714 1/20 0.51
▸ L3MBTL1 Q9Y468 2/20 0.51
▸ MAPT P10636 1/20 0.51
▸ CYP2C9 P11712 1/20 0.51
▸ CYP2C19 P33261 1/20 0.51
▸ TDP1 Q9NUW8 1/20 0.51
▸ SMPD1 P17405 1/20 0.51
▸ HDAC1 Q13547 1/20 0.51
▸ HDAC8 Q9BY41 1/20 0.51
▸ HDAC6 Q9UBN7 1/20 0.51
▸ ALDH1A1 P00352 1/20 0.50
▸ HTT P42858 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7009118 0.87 MAOB (0.66) CREBBPMAOBSMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL3123036 0.86 MAOB (0.64) MAOBMRGPRX4SMN1; SMN2NPC1RAB9A
SCHEMBL15754863 0.86 HPGD (0.58) SMN1; SMN2NPC1RAB9AHPGDUSP2
SCHEMBL27396917 0.86 SMN1; SMN2 (0.71) CREBBPMAOBMRGPRX4SMN1; SMN2NPC1
SCHEMBL11088894 0.84 KMT2A (0.57) SMN1; SMN2NPC1RAB9AHPGDUSP2
Acetic Acid SCHEMBL9653704 0.84 SMN1; SMN2 (0.52) MAOBSMN1; SMN2NPC1RAB9AHPGD
SCHEMBL29783148 0.84 FFAR4 (0.62) MAOBMRGPRX4SMN1; SMN2NPC1RAB9A
SCHEMBL1545310 0.84 EGFR (0.64) MAOBMRGPRX4SMN1; SMN2NPC1RAB9A
SCHEMBL29803481 0.84 EGFR (0.64) MAOBMRGPRX4SMN1; SMN2NPC1RAB9A
SCHEMBL385027 0.84 FFAR4 (0.62) MAOBMRGPRX4SMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119390668-A Compound with ketoxime ether structure and application thereof 复旦大学 2025-02-07 — — CN disclosed
US-11286235-B2 Ultra short acting anti-arrhythmic agents Academic Pharmaceuticals, Incorporated (US) 2022-03-29 — — US disclosed
US-20210107867-A1 ULTRA SHORT ACTING ANTI-ARRHYTHMIC AGENTS ACADEMIC PHARMACEUTICALS INCORPORATED 2021-04-15 — — US disclosed
WO-2016001452-A1 COMPOUNDS, IN PARTICULAR FOR USE IN THE TREATMENT OF A DISEASE OR CONDITION FOR WHICH A BROMODOMAIN INHIBITOR IS INDICATED Universität Zürich (CH) 2016-01-07 — — WO disclosed
US-7964628-B2 Fibrinogen receptor antagonists and their use PIRAMAL LIFE SCIENCES LIMITED (IN) 2011-06-21 — — US disclosed
US-20100256161-A1 FIBRINOGEN RECEPTOR ANTAGONISTS AND THEIR USE PIRAMAL LIFE SCIENCES LIMITED (IN) 2010-10-07 — — US disclosed
US-7759387-B2 Fibrinogen receptor antagonists and their use PIRAMAL LIFE SCIENCES LIMITED (IN) 2010-07-20 — — US disclosed
US-20070021489-A1 Fibrinogen receptor antagonists and their use NICHOLAS PIRAMAL INDIA LIMITED (IN) 2007-01-25 — — US disclosed
EP-1677783-A2 FIBRINOGEN RECEPTOR ANTAGONISTS AND THEIR USE Nicholas Piramal India Limited (IN) 2006-07-12 — — EP disclosed
US-7022716-B2 Cyclic amine phenyl beta-3 adrenergic receptor agonists WYETH (US) 2006-04-04 — — US disclosed
EP-0080595-A1 Alkanesulfonanilide derivatives and pharmaceutically acceptable acid addition salts thereof AMERICAN CYANAMID COMPANY (US) 1983-06-08 — — EP disclosed
US-4254117-A BACTERICIDES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1981-03-03 — — US disclosed
US-4143166-A ANTIBIOTICS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1979-03-06 — — US disclosed
US-4038314-A CASODILATORS, CARDIOTONICS, BRONCHOLYTICS BOEHRINGER INGELHEIM GMBH (DT) 1977-07-26 — — US disclosed
US-4024281-A N,N-bis[2-(3-substituted-4-hydroxyphenyl)-ethyl or -2-hydroxyethyl]-polymethylenediamines SMITHKLINE CORPORATION (US) 1977-05-17 — — US disclosed
US-3996383-A 3-Alkylamino-α-aminomethyl-4-hydroxybenzyl alcohols with β-adrenergic stimulant activity SMITHKLINE CORPORATION (US) 1976-12-07 — — US disclosed
US-3994974-A BRONCHODILATORS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) 1976-11-30 — — US disclosed
US-3943173-A 3-Alkylamino- alpha-aminomethyl-4-hydroxybenzyl alcohols SMITHKLINE CORPORATION (US) 1976-03-09 — — US disclosed
US-3943254-A ALPHA-AMINOMETHYL-4-HYDROXY-3-SULFAMYL BENZYL ALCOHOLS OR 4-HYDROXY-3-SULFAMYL-PHENETHYLAMINE SMITHKLINE CORPORATION (US) 1976-03-09 — — US disclosed
US-3933913-A N,N'-bis[3-substituted-4-hydroxypheyl)-2-hydroxyethyl)]-polymethylenediamines SMITHKLINE CORPORATION (US) 1976-01-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256161-A1 FIBRINOGEN RECEPTOR ANTAGONISTS AND THEIR USE FGB, F13B, F2 CREBBP 3449/4885MAOB 1394/4885MRGPRX4 653/4885
US-20210107867-A1 ULTRA SHORT ACTING ANTI-ARRHYTHMIC AGENTS SCN5A, CACNA1G, CACNA1H CREBBP 4688/4885MAOB 2237/4885MRGPRX4 2059/4885
US-20070021489-A1 Fibrinogen receptor antagonists and their use FGB, F13B, F2 CREBBP 3449/4885MAOB 1394/4885MRGPRX4 653/4885
US-11286235-B2 Ultra short acting anti-arrhythmic agents SCN5A, CACNA1G, CACNA1H CREBBP 4688/4885MAOB 2237/4885MRGPRX4 2059/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.