Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 7/20 | 0.44 |
| ▸ | CTSK | P43235 | 7/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2682024 | 0.87 | MEN1 (0.51) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL5019146 | 0.87 | CTSS (0.54) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL1854217 | 0.87 | MEN1 (0.51) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL3544394 | 0.87 | CTSS (0.54) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL1626495 | 0.87 | CTSS (0.54) | MEN1GAAKMT2ACTSSCTSK | |
| Hydrochloric Acid SCHEMBL2681084 | 0.86 | MEN1 (0.50) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL10475827 | 0.84 | MEN1 (0.49) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL6936247 | 0.84 | MEN1 (0.49) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL29398196 | 0.84 | MEN1 (0.49) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL10475828 | 0.84 | MEN1 (0.49) | MEN1GAAKMT2ACTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7396859-B2 | Perturbed membrane-binding compounds | NST NEUROSURVIVAL TECHNOLOGIES, LTD. (IL) | 2008-07-08 | — | — | US | disclosed |
| US-7396859-B2 | Perturbed membrane-binding compounds | NST NEUROSURVIVAL TECHNOLOGIES, LTD. (IL) | 2008-07-08 | — | — | US | disclosed |