Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.84 |
| ▸ | MMP12 | P39900 | 1/20 | 0.84 |
| ▸ | NR1I2 | O75469 | 8/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3086979 | 1.00 | PRKCA (0.84) | PRKCAMMP12NR1I2CYP3A4CYP2C9 | |
| SCHEMBL14110710 | 0.95 | PRKCA (0.81) | PRKCAMMP12NR1I2CYP3A4CYP2C9 | |
| SCHEMBL396059 | 0.92 | PRKCA (0.72) | PRKCAMMP12NR1I2CYP3A4CYP2C9 | |
| SCHEMBL2274295 | 0.91 | PRKCA (0.88) | PRKCAMMP12NR1I2CYP3A4CYP2C9 | |
| Mk-3281 SCHEMBL29399714 | 0.91 | PRKCA (1.00) | PRKCAMMP12NR1I2CYP3A4CYP2C9 | |
| Mk-3281 SCHEMBL31554854 | 0.91 | PRKCA (1.00) | PRKCAMMP12NR1I2CYP3A4CYP2C9 | |
| Mk-3281 SCHEMBL3073622 | 0.91 | PRKCA (1.00) | PRKCAMMP12NR1I2CYP3A4CYP2C9 | |
| Mk-3281 SCHEMBL3088843 | 0.91 | PRKCA (1.00) | PRKCAMMP12NR1I2CYP3A4CYP2C9 | |
| SCHEMBL4210853 | 0.91 | PRKCA (0.86) | PRKCAMMP12NR1I2CYP3A4CYP2C9 | |
| SCHEMBL4221579 | 0.90 | PRKCA (0.75) | PRKCAMMP12NR1I2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121707-B1 | ANTIVIRAL INDOLES | ANGELETTI P IST RICHERCHE BIO (IT) | 2012-12-05 | — | — | EP | disclosed |